With the arrival of Industry 4.0, interoperability has become a major subject for companies worldwide. It is a crucial asset that enables new technologies and possibilities (Industrial Internet of Things, predictive maintenance or traceability solutions). With the increasing importance of data in business use cases, companies are faced with a choice between two interoperability approaches to deal with the challenge of reconciling different domains: standardization and mediation. This paper presents an analysis of each approach and proposes a decision-making methodology based on the Analytic Hierarchy Process (AHP) that aims to help companies in choosing the most suitable solution to resolve interoperability challenges.