Course of acute nonspecific mesenteric lymphadenitis: single-center experience

Abstract

In patients affected with acute nonspecific mesenteric lymphadenitis, it is advantageous to think of the time span for recovery in terms of ≥ 4 weeks. What is Known: • Mesenteric adenitis is a self-limiting inflammatory condition with well-characterized clinical presentation and imaging features. • A total duration of symptoms of ≤ 4 weeks is usually hypothesized. What is New: • Symptoms persist for 3 to 10 weeks in half of the patients. • At presentation, clinical and laboratory characteristics are similar in children with symptoms persisting for 2 weeks or less and in those with 45 symptoms persisting for 3-10 weeks.

Reference intervals of mesenteric lymph node size according to lymphocyte counts in asymptomatic children

“…With the estimated reference intervals of the size of LMLN established in this study, the short-axis diameter greater than 8-10 mm could be used as the diagnostic criterion for primary mesenteric lymphadenitis based on the presence of a cluster of three or more mesenteric lymph nodes and in the absence of other abnormalities [2,5,7,19]. Furthermore, the diagnosis of mesenteric lymphadenitis relies on imaging, medical history, and clinical features [20][21][22][23]. It is particularly important that the identification of MLNE should not preclude the search for additional abdominal or pelvic abnormalities, as the erroneous attribution of enlarged mesenteric lymph nodes to mesenteric lymphadenitis has a potential risk of missing other acute diseases, such as acute appendicitis, intussusception, torsion of the ovary and so on, which require emergent surgical treatments [2,8,24].…”

Acute fulminant necrotizing mesenteric lymphadenitis causing bowel ischemia

“…Mesenteric lymphadenitis commonly occurs in children and is an inflammatory and self-limited disease, which usually resolves within 4 weeks [1]. Although rare in adults, infectious lymphadenitis can progress to complete necrosis of the mesenteric lymph nodes if the infection is due to tuberculosis, Yersinia or salmonella infection [2].…”