Course of Skin Symptoms and Quality of Life in Children Referred for Patch Testing – A Long-term Follow-up Study

Simonsen, Anne Birgitte; Sommerlund, Mette; Deleuran, Mette; Mørtz, Charlotte G.; Johansen, Jeanne Duus

doi:10.2340/00015555-1911

Cited by 8 publications

(12 citation statements)

References 18 publications

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“…High scores of the item on ‘restrictions and limitations’ in children with ACD and AD are a result of the so-called avoiding strategy. Difficulties in adopting suitable avoidance behaviour by patients who were diagnosed with ACD is a well-known problem [ 24 ]. Therefore a high score for ‘restrictions and limitations’ in children with ACD may reflect an adequate avoiding strategy provided by their parents.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life of Infants, Toddlers and Preschoolers with Seborrhoeic, Allergic Contact and Atopic Dermatitis Before and During COVID-19 Pandemic

Chernyshov

Возіанова

Chubar

2021

Dermatol Ther (Heidelb)

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Introduction Different aspects of quality of life (QoL) of infants and children with atopic dermatitis (AD) are well studied but there is a lack of studies on seborrhoeic dermatitis (SD) and allergic contact dermatitis (ACD). The aim of this study was to compare the impact of SD, ACD and AD on young children. Parts of questionnaires were filled in during the COVID-19 pandemic and therefore we decided to check if the pandemic affected dermatology-specific health-related quality of life (HRQoL) in our patients. Methods In this cross-sectional study approved by the local ethics committee of the Kiev City Clinical Dermatovenereologic Hospital parents of children with SD, ACD and AD from birth to 4 years old from the same department of dermatology were asked to fill in the dermatology-specific questionnaire the Infants and Toddlers Dermatology Quality of Life (InToDermQoL). Diagnoses were based on clinical manifestations and anamnesis. The study was carried out from 2018 till 2021. Results The InToDermQoL questionnaire was filled in by 176 parents of children with SD, ACD and AD. Mean total InToDermQoL scores were significantly higher in children with AD than in SD and ACD ( P < 0.01). HRQoL of children with AD during the COVID-19 pandemic was significantly worse than before pandemic (41.30 ± 24.40 and 28.51 ± 17.67 respectively, P = 0.02). Scores of the item on ‘sleep problems’ significantly decreased during the COVID-19 pandemic in children with SD (1.19 ± 1.01 and 0.64 ± 0.63, P < 0.05), as did scores of the item on ‘rejection by other children’ in children with AD (0.96 ± 0.98 and 0.20 ± 0.45, P < 0.05). Conclusions To the best of our knowledge this is the first study on HRQoL of the youngest children with SD and ACD. In our study children with SD and ACD had comparable but lower impact of skin disease on their HRQoL than children with AD. The COVID-19 pandemic led to more severe HRQoL impairment in patients with AD visiting a dermatology department.

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Section: Discussionmentioning

confidence: 99%

Quality of Life of Infants, Toddlers and Preschoolers with Seborrhoeic, Allergic Contact and Atopic Dermatitis Before and During COVID-19 Pandemic

Chernyshov

Возіанова

Chubar

2021

Dermatol Ther (Heidelb)

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“…Children with ACD have worsened quality of life measures such as reduced sleep quality, impaired school performance, and problems with friends or relatives. 136 Younger children with ACD were found to have lower occupational and functional quality of life scores compared to older children. 137 Validated ACD-specific questionnaires have shown that the emotional aspect of the disease is most burdensome, a measure that improved months after allergen avoidance.…”

Section: Quality Of Lifementioning

confidence: 97%

Pediatric allergic contact dermatitis. Part I: Clinical features and common contact allergens in children

Neale

Garza-Mayers

Tam

et al. 2021

Journal of the American Academy of Dermatology

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Allergic contact dermatitis (ACD), a delayed hypersensitivity skin reaction to environmental allergens, has a prevalence that is similar in children and adults. However, diagnostic testing for ACD in pediatric populations accounts for less than one tenth of all patch tests. The relative infrequency of pediatric patch testing may be attributed to the difficulty in testing in this population, which includes a smaller surface area for patch test placement and maintaining cooperation during patch testing, especially in younger children. Diagnosis can be difficult in children because the appearance of ACD can mimic other common pediatric skin conditions, particularly atopic dermatitis and irritant contact dermatitis. Comprehensive history taking, guided by patient presentation, age group, and location of dermatitis, helps build clinical suspicion. Such clinical suspicion is one of the major reasons behind patch testing, with additional indications being recalcitrant dermatitis and dermatitis with atypical distribution. US pediatric data have shown the top allergens to be metals, fragrances, topical antibiotics, preservatives, and emollients. These trends are important to recognize to guide management and accurate diagnosis, because ACD tends to persist if the allergen is not identified and can affect patients' quality of life.

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“…All but one of these modifications extended the 1-week recall period of the original DLQI. Of these, LY-DLQI was the most common by having been used in 7 independent studies, 43,[79][80][81][82][83][84] and another 2 studies (4 publications) 45,[85][86][87] applied a 1-year recall period along with other modifications made. The LY-DLQI allows to capture the long-term HRQoL impact of skin diseases as well as to compare scores with those of the original DLQI.…”

Section: Discussionmentioning

confidence: 99%

Questionnaire Modifications and Alternative Scoring Methods of the Dermatology Life Quality Index: A Systematic Review

2021

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Objectives: Dermatology Life Quality index (DLQI) is the most widely used health-related quality of life questionnaire in dermatology. Little is known about existing questionnaire or scoring modifications of the DLQI. We aimed to systematically review, identify, and categorize all modified questionnaire versions and scoring methods of the DLQI.Methods: We performed a systematic literature search in PubMed, Web of Science, CINAHL, and PsychINFO. Methodologic quality and evidence of psychometric properties were assessed using the Consensus-Based Standards for the Selection of Health Measurement Instruments (COSMIN) and Terwee checklists. Results:The included 81 articles reported on 77 studies using 59 DLQI modifications. Modifications were used for a combined sample of 25 509 patients with 47 different diagnoses and symptoms from 28 countries. The most frequently studied diseases were psoriasis, hirsutism, acne, alopecia, and bromhidrosis. The modifications were categorized into the following nonmutually exclusive groups: bolt-ons or bolt-offs (48%), disease, symptom, and body part specifications (42%), changes in existing items (34%), scoring modifications (27%), recall period changes (19%), response scale modifications (15%), and illustrations (3%). The evidence concerning the quality of measurement properties was heterogeneous: 4 of 13 studies were rated positive on internal consistency, 1 of 3 on reliability, 3 of 5 on content validity, 9 of 22 on construct validity, 6 of 6 on criterion validity, and 1 of 1 on responsiveness. Conclusion:An exceptionally large number of DLQI modifications have been used that may indicate an unmet need for adequate health-related quality of life instruments in dermatology. The psychometric overview of most questionnaire modifications is currently incomplete, and additional efforts are needed for proper validation.

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Course of Skin Symptoms and Quality of Life in Children Referred for Patch Testing – A Long-term Follow-up Study

Cited by 8 publications

References 18 publications

Quality of Life of Infants, Toddlers and Preschoolers with Seborrhoeic, Allergic Contact and Atopic Dermatitis Before and During COVID-19 Pandemic

Quality of Life of Infants, Toddlers and Preschoolers with Seborrhoeic, Allergic Contact and Atopic Dermatitis Before and During COVID-19 Pandemic

Pediatric allergic contact dermatitis. Part I: Clinical features and common contact allergens in children

Questionnaire Modifications and Alternative Scoring Methods of the Dermatology Life Quality Index: A Systematic Review

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