The underrepresentation of females in certain fields has been studied extensively in many countries. Similar to other parts of the World, the number of females graduating each year from universities in the Arab World now exceeds the number of males, yet gender differences in educational fields persist. The objective of this study is to review the extant literature on the gender gap in science, technology, engineering, and mathematics (STEM) in the Arab World. The review synthesizes the findings of 86 articles that were published in journals and conference proceedings. This review explores gender differences in mathematics performance, math anxiety, self-concept, and occupational career choices. The review also explores social barriers that contribute to the underrepresentation of females in STEM fields. The study highlights differences between results obtained in the Arab World and results obtained in Western countries while also noting the differences between the Arab countries themselves. Finally, the study suggests directions for future research.