Covalently attachment of aliphatic linear non-branched alcohols to silicon oxide and glass substrates in liquid paraffin solvent

In this pandemic SARS-CoV-2 crisis, any attempt to contain and eliminate the virus will also stop its spread and consequently decrease the risk of severe illness and death. While ozone treatment has been suggested as an effective disinfection process, no precise mechanism of action has been previously reported. This study aimed to further investigate the effect of ozone treatment on SARS-CoV-2. Therefore, virus collected from nasopharyngeal and oropharyngeal swab and sputum samples from symptomatic patients was exposed to ozone for different exposure times. The virus morphology and structure were monitored and analyzed through Atomic Force Microscopy (AFM), Transmission Electron Microscopy (TEM), Atomic Absorption Spectroscopy (AAS), and ATR-FTIR. The obtained results showed that ozone treatment not only unsettles the virus morphology but also alters the virus proteins’ structure and conformation through amino acid disturbance and Zn ion release from the virus non-structural proteins. These results could provide a clearer pathway for virus elimination and therapeutics preparation.

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Destruction mechanisms of ozone over SARS-CoV-2

Ataei‐Pirkooh

Alavi

Kianirad

et al. 2021

Sci Rep

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Covalently attachment of aliphatic linear non-branched alcohols to silicon oxide and glass substrates in liquid paraffin solvent

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Destruction mechanisms of ozone over SARS-CoV-2

Destruction mechanisms of ozone over SARS-CoV-2

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