Cover Feature: Magnetic Hybrid Wax Nanocomposites as Externally Controlled Theranostic Vehicles: High MRI Enhancement and Synergistic Magnetically Assisted Thermo/Chemo Therapy (Chem. Eur. J. 20/2020)

Abstract

Theranostic magnetic wax nanocomposite vehicles were synthesized through a safe‐by‐design approach which simultaneously incorporated magnetic nanoparticles and the anticancer drug Oncocalyxone A. The obtained formulation showed outstanding performance as a T2‐contrast agent in MRI and offered a synergistic thermo/chemotherapeutic effect in vitro derived from heat generation by magnetic hyperthermia and controlled drug delivery over cancer growth. This external control over the drug delivery profile and the integrated imaging capability open the door to personalized cancer medicine and real‐time monitoring of tumor progression. More information can be found in the Full Paper by M. Bañobre‐López et al. on page 4531.