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Miripour, Zohreh Sadat; Abbasvandi, Fereshteh; Aghaee, Parisa; Shojaeian, Fatemeh; Faramarzpour, Mahsa; Mohaghegh, Pooneh; Hoseinpour, Parisa; Namdar, Naser; Amiri, Mojtaba; Ghafari, Hadi; Parniani, Mohammad; Kaviani, Ahmad; Alamdar, Sedigheh; Najafikhoshnoo, Sahar; Sanati, Hassan; Mapar, Mahna; Sadeghian, Nastaran; Akbari, Mohammad Esmaeil; Yunesian, Masud; Abdolahad, Mohammad

doi:10.1002/cam4.4723

Cited by 2 publications

(1 citation statement)

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“…LA is an indicator of metabolic disorder status under anaerobic conditions and provides useful information on various diseases or symptoms, such as tissue hypoxia, sepsis, acute heart disease, and metabolic acidosis, as well as exercise training status. [17,18] In addition, as the LA concentration in blood is reflected in the LA concentration of sweat, LA can be profiled indirectly through a non-invasive method. [19] Therefore, various types of organic chemical sensors, which can detect LA concentrations, have been developed such as electrochemical, [20] optical, [21] impedance, [22] capacitive, [23] and transistor-structured applications.…”

Section: Introductionmentioning

confidence: 99%

Exploration on Solvatochromic Sensing Probe of Phenol Blue for L‐Lactic Acid Detection: Effective Strategy to Obtain Reliable Capacitive Sensor

Seo

Hwang

et al. 2022

Adv Funct Materials

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This study systematically investigates a capacitive sensor applied with phenol blue (PhB)-based sensing medium for detection of L-lactic acid (LA), as a health monitoring indicator. PhB is a substance with solvatochromic effect, inducing the change in capacitance by exposure to polar molecules. However, the capacitive LA sensor with a flat-structured PhB/polyvinylchloride (PVC) composite-sensing medium is observed to have a problem in that sensing capacitance variation saturate quickly with increasing the LA solution concentration. This main cause can be analyzed that the interaction of proton from LA molecule with the lone pair electrons of the PhB molecule acts as a major factor on the sensing characteristics rather than the solvatochromic behavior of PhB molecule. Therefore, a strategy is adopted to introduce a porous structure to the PhB/PVC composite-sensing medium to maximize the interaction of PhB with protons, which is implemented through solvent and non-solvent exchange methods. Consequently, the sensitivity and linearity of the porous-structured LA sensor are 2.99 pF mm −1 and 0.966 over LA concentrations ranging from 0 to 100 mm, respectively, which is a significant improvement over that of the flat-structured one. Notably, the sensing performance remained unchanged even after a month of storage under normal ambient conditions.

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Section: Introductionmentioning

confidence: 99%

Exploration on Solvatochromic Sensing Probe of Phenol Blue for L‐Lactic Acid Detection: Effective Strategy to Obtain Reliable Capacitive Sensor

Seo

Hwang

et al. 2022

Adv Funct Materials

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Clinical validation on role of cancer diagnostic probe in detecting the involved cavity margins missed in permanent pathology of tumor side in breast cancer surgery

Abbasvandi,

Miripour,

Bayat

et al. 2024

Diagn Pathol

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Cancer diagnostic probe (CDP) as a newly entered tool in real-time breast cavity margin evaluation showed great improvement in smart margin shaving intra-operatively. This system increased the rate of involved margin detection to 30% with respect to frozen section. In this study for the first time we showed the independent role of CDP in finding the involved cavity side margins which were not diagnosed by permananet pathology of their tumor side interface. Among 147 detected margins by CDP, 23 lesions with invasive component and ductal carcinoma in-situ/ ductal cancerization weren't reported as involved margins in permanent pathology of tumor side. Our gold standard was the histology of cavity margin specimen had been scored as involved lesion by CDP. It seems that even when the permanent pathology of surgical margins is used for final declaration, role of CDP is irreplaceable. This distinguished achievement has been obtained intra-operatively in real-time by CDP while involved report in permanent pathology of tumor margins induce re-surgery for the patient.

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Cited by 2 publications

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Exploration on Solvatochromic Sensing Probe of Phenol Blue for L‐Lactic Acid Detection: Effective Strategy to Obtain Reliable Capacitive Sensor

Exploration on Solvatochromic Sensing Probe of Phenol Blue for L‐Lactic Acid Detection: Effective Strategy to Obtain Reliable Capacitive Sensor

Clinical validation on role of cancer diagnostic probe in detecting the involved cavity margins missed in permanent pathology of tumor side in breast cancer surgery

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