COVID-19 and acute limb ischemia: a systematic review

COVID-19 pandemisinde doğal kapak endokarditinin ilk belirtisi: Alt ekstremitede akut arteriyel septik emboli

“…Several studies have shown that COVID-19 patients whose coagulation parameters were abnormal were more likely to have a worse prognosis. According to the available literature, coagulopathy in COVID-19 infections may manifest as acute limb ischemia (6,7). Patients with infectious endocarditis may also have symptoms similar to COVID-19 infection like fever, anorexia, weakness, headache, myalgia, arthralgia, dyspnea, and acute limb ischemia as mentioned above.…”

How the First Year of the COVID-19 Pandemic Impacted Patients’ Hospital Admission and Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

“…The VASCC is a combined international effort to obtain prospective data on the impact of widespread vascular surgical care delays due to an international crisis or pandemic [ 8 , 9 ]. An increased rate of DVT during the first four months of the pandemic and of hospitalization for thrombotic acute lower limb ischemia recalls the prothrombotic effects of the SARS-CoV-2 infection [ 10 , 11 ]. This broad spectrum of clinical manifestations, affecting almost all organs and systems, is a consequence of endothelial dysfunction and systemic inflammatory response.…”

“…(3) duplex or computed-tomography scans performed for post-EVAR surveillance; (4) Previous EVAR treated again (in an open or endovascular fashion) for recurring symptomatic or ruptured AAA, or for endoleak at risk of AAA rupture (type 1, 3, or 2 with sac expansion); (5) open, or endovascular treatments for thrombotic, non-embolic, acute lower limb ischemia; (6) treatments for Rutherford category 3 peripheral arterial disease (R3-PAD) in socially active patients with very short distance intermittent claudication (less than 50 mt. on the flat), not responsive to best medical therapy, and asking for a resolutive treatment to improve their lifestyle; (7) open or endovascular revascularizations for chronic limb-threatening ischemia (CLTI); (8) CLTI patients who have had a thigh or leg amputated; (9) open or endovascular revascularizations for asymptomatic severe internal carotid artery (ICA) stenosis; (10) Asymptomatic severe ICA stenosis on surgical waiting list, complicated to total obstruction (with or without neurological symptoms); (11) symptomatic ICA stenosis operated in urgency; (12) conservative or surgical treatments for venous ulcers; (13) diagnosis of deep vein thrombosis (DVT), also from requests of consultation from the emergency room or any medical/surgical divisions.…”

Outcomes of Surgical Revascularization for Acute Limb Ischemia in COVID-19 Patients Comparing to Noninfected Cohort: A Single-Center Observational Prospective Study

“…Association of coronavirus infection disease (COVID-19) with acute thrombotic events, in particular with ALI, was observed from the beginning of the “first wave” of pandemic [ 4 , 5 ]. Early experience in the management of patients with ALI and COVID-19 uncovered dismal results of treatment with unusually high rates of re-intervention (around 13%), amputation (> 30%) and death (>35%) [ 5 , 6 , 7 ]. In the amid of pandemic the European Society for Vascular Surgery published an update of clinical practice guideline on the management of ALI in patients with COVID-19, based on the analysis of limited number of publications: 89 case reports and nine cohort studies reporting on 13-49 patients.…”