With the advent of the ‘age of conspiracism’, the harmfulness of conspiratorial narratives and mindsets on individuals’ mentalities, on social relations, and on democracy, has been widely researched by political scientists and psychologists. One known negative effect of conspiracy theories is the escalation toward political radicalism. This study goes beyond the exploration of mechanisms underpinning the relationship between conspiracy theory and radicalization to focus on possible approaches to mitigating them. This study sheds light on the role of counter-conspiracy approaches in the process of deradicalization, adopting the case study of anti-China sentiment and racial prejudice amid the Covid-19 pandemic, through conducting an experiment (
N
= 300). The results suggest that, during critical events such as the Covid-19 pandemic, exposure to countermeasures to conspiracist information can reduce individual acceptance of radicalism. We investigated two methods of countering conspiracy theory, and found that: (1) a content-targeted ‘inoculation’ approach to countering conspiracy theory can prevent the intensification of radicalization, but does not produce a significant deradicalization effect; and (2) an audience-focused ‘disenchantment’ method can enable cognitive deradicalization, effectively reducing the perception of competitive victimhood, and of real and symbolic threats. This study is one of the first attempts to address causality between deradicalization and countermeasures to conspiracy theories in the US-China relations.