2021
DOI: 10.35772/ghm.2020.01117
|View full text |Cite
|
Sign up to set email alerts
|

COVID-19 and bronchial asthma: current perspectives

Abstract: Angiotensin converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2), two receptors on the cell membrane of bronchial epithelial cells, are indispensable for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. ACE2 receptor is increased among aged, males, and smokers. As smoking upsurges ACE2 expression, chronic obstructive pulmonary disease (COPD) patients are prone to SARS-CoV-2 infection, and are at a higher risk for severe forms of COVID-19 (coronavirus disease 2019) onc… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
2
1
2

Year Published

2021
2021
2024
2024

Publication Types

Select...
8

Relationship

2
6

Authors

Journals

citations
Cited by 10 publications
(5 citation statements)
references
References 41 publications
0
2
1
2
Order By: Relevance
“…Epidemiologically, patients with asthma are less likely to suffer from COVID-19. [19] The incidence of asthma and chronic obstructive pulmonary disease was not significantly higher in the variant (+) group in our study.…”
Section: Discussioncontrasting
confidence: 55%
“…Epidemiologically, patients with asthma are less likely to suffer from COVID-19. [19] The incidence of asthma and chronic obstructive pulmonary disease was not significantly higher in the variant (+) group in our study.…”
Section: Discussioncontrasting
confidence: 55%
“…However, they may not have been as prevalent when hypertension was the sole comorbidity, and a lower proportion of individuals may have made efforts to mitigate the risk of severe outcomes. Additionally, the regulation of angiotensin converting enzyme 2 expression has been associated with various factors, including obesity, sex, asthma, and hypertension [ 15 , 16 ], suggesting an influence on the relationship between asthma and hypertension observed in this study. A higher proportion of patients with COPD were vaccinated against COVID-19, which may be attributed to the prioritized vaccination of older adults in Japan.…”
Section: Discussionmentioning
confidence: 74%
“…В перечне сопутствующих бронхолегочных заболеваний у 11,1 % из наших пациентов имелась бронхиальная астма различной степени тяжести, но ее наличие также не влияло на изменение ФВ ЛЖ и СДЛА, что соответствует результатам обзорного эпидемиологического исследования, проведенного в 2021 г. M. Hojo и соавт. [18].…”
Section: Discussionunclassified