COVID-19 and Diabetes in Children: A Narrative Review

Abstract

Background: COVID-19 is an unknown and novel virus that creates a challenge with all comorbid conditions, including diabetes mellitus (DM). Although DM has not been determined as a definite risk factor for COVID-19 in childhood, clinicians should consider the potential association between DM and COVID-19. Objectives: This study aimed to review COVID-19 and DM comorbidity in children. Methods: ISI Web of Science, PubMed, and Google Scholar were investigated to find relevant articles regarding COVID-19 and DM. Results: Data revealed 50% higher fatal outcomes of COVID-19 in DM children than in healthy ones. Because of the importance of DM in children, it seems mandatory to consider type 1 diabetes and its consequences on COVID-19. Conclusions: Understanding the pathophysiology of COVID-19 and its interaction with DM are helpful for better management of the disease. These considerations can help clinicians make better decisions about the treatment modalities, management, and diabetic ketoacidosis treatment.

The therapeutic, preventive, and immune-boosting effects of some minerals and vitamins in COVID-19: A narrative review

“…The clinical characteristics of COVID-19 are categorized into five distinct types as follows (5) (6).…”

Efficacy of N‑Acetylcysteine in Children with Moderate COVID-19: A Placebo-Controlled Randomized Clinical Trial

“…The coronavirus disease 2019 (COVID- 19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, has resulted in lung failure and the need for mechanical ventilation (1)(2)(3). Initially, during the early stages of the COVID-19 pandemic, the incidence of positive cases among children was deemed negligible, and it was assumed that children were less susceptible (4)(5)(6). However, subsequent studies have indicated that children and adolescents are also vulnerable to SARS-CoV-2 infection.…”