Covid-19 and hypokalaemia – A potential mechanism

Mandal, Amit K J; Kho, Jason; Metaxa, Sofia; Missouris, Constantinos G

doi:10.1177/0004563220973497

Cited by 1 publication

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 Throughout the pandemic, concerns were raised about COVID-19 infection-related electrolyte disturbances on patients with skeletal muscle channelopathies. 3,4 In addition, the side-effect profile of COVID-19 vaccination in patients with channelopathies is unknown. 5 Because of concerns over the risk of venous or arterial thromboembolism with some vaccines, the risk profile is unclear in patients with channelopathies who have impaired ambulation or may be more sedentary.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

COVID‐19 infection and vaccination in patients with skeletal muscle channelopathies

Vivekanandam¹,

Jayaseelan²,

Hanna³

2022

Muscle and Nerve

View full text Add to dashboard Cite

Introduction/Aims Although we have gained insight into coronavirus disease‐2019 (COVID‐19) caused by severe acute respiratory syndrome–coronavirus 2 since the beginning of the pandemic, our understanding of the consequences for patients with neuromuscular disorders is evolving. In this study we aimed to study the impact of COVID‐19 and COVID‐19 vaccination on skeletal muscle channelopathies. Methods We conducted a survey of patients with genetically confirmed skeletal muscle channelopathies seen at the UK Nationally Commissioned Channelopathy Service. Results Thirty‐eight patient responses were received. Six patients had COVID‐19 infection leading to exacerbation of their underlying muscle channelopathy. No major complications were reported. Thirty‐six patients had received one or two COVID‐19 vaccinations and the majority (68%) had no worsening of their underlying channelopathy. Thirty‐two percent reported worsening of their usual symptoms of their muscle channelopathy, but all reported recovery to baseline levels. No serious adverse events were reported. Discussion The overall rates of COVID‐19 infection were low in our study and COVID‐19 vaccine uptake rates were high. Our results have been useful to inform patients that a subset of patients have reversible worsening of their channelopathy post–COVID‐19 vaccination. Our study provides information for giving advice to patients with skeletal muscle channelopathies regarding COVID‐19 infection and vaccination.

show abstract

Section: Introductionmentioning

confidence: 99%

“…Throughout the pandemic, concerns were raised about COVID‐19 infection–related electrolyte disturbances on patients with skeletal muscle channelopathies 3,4 . In addition, the side‐effect profile of COVID‐19 vaccination in patients with channelopathies is unknown 5 .…”

Section: Introductionmentioning

confidence: 99%