2022
DOI: 10.1007/s11547-022-01500-w
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COVID-19 and low back pain: previous infections lengthen recovery time after intradiscal ozone therapy in patients with herniated lumbar disc

Abstract: Purpose To assess and compare the clinical effectiveness of percutaneous intradiscal ozone therapy in patients affected by lumbar disc herniation, with and without history of COVID-19 infection. Materials and Methods After the rising of COVID-19 pandemics in Italy, 47 consecutive percutaneous intradiscal ozone therapies were performed on patients with low back pain and/or sciatic pain due to lumbar disc herniation. Among these, 19 had suffered from COVID-19 and successi… Show more

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Cited by 10 publications
(6 citation statements)
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“…The intervention results in an augmentation of oxygen delivery to the intervertebral disc, eliciting a stimulation of cellular proliferation and production of extracellular matrix components, ultimately facilitating the process of tissue healing. Francesco Somma conducted a study wherein the Oswestry Disability Index (ODI) showed a substantial reduction among patients with disc herniation who had previously been infected with the novel coronavirus following ozone therapy ( Somma et al., 2022 ).…”
Section: Treatment Of Septic Inflammationmentioning
confidence: 99%
“…The intervention results in an augmentation of oxygen delivery to the intervertebral disc, eliciting a stimulation of cellular proliferation and production of extracellular matrix components, ultimately facilitating the process of tissue healing. Francesco Somma conducted a study wherein the Oswestry Disability Index (ODI) showed a substantial reduction among patients with disc herniation who had previously been infected with the novel coronavirus following ozone therapy ( Somma et al., 2022 ).…”
Section: Treatment Of Septic Inflammationmentioning
confidence: 99%
“…The pandemic has also necessitated the development of models to support clinical practice using artificial intelligence (AI) techniques [ 91 , 92 , 93 , 94 ]. Currently, the supporting models reported in the literature regarding COVID-19 have mainly focused on epidemic trends, early screening, and CT diagnosis as well as prognosis [ 95 , 96 , 97 , 98 , 99 , 100 ].…”
Section: Sex Differences In Respiratory Pathologiesmentioning
confidence: 99%
“…With regard to treatment-related pneumonitis chest radiography, due to its low specificity, it can be used as a screening investigation, while the role of PET is still unclear due to the potential overlap of the metabolic activity of infectious processes with malignant tumors. Chest CT allows early parenchymal changes and their evolution to be evaluated, thus representing the gold standard for the study of lung parenchyma [ 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 ]. Nevertheless, diagnosis is complicated due to the overlapping of the various CT patterns, and in this scenario, we should consider radiation pneumonia (RP), pneumonia by immune checkpoint inhibitors (CIP) and the possibility that the lung involvement is due to disease progression that may be manifested as pulmonary lymphangitis [ 89 ].…”
Section: Diagnostic Managementmentioning
confidence: 99%