COVID-19 and severe rhabdomyolysis causing acute kidney injury and life-threatening hyperkalemia: A case report

Abstract

Introduction Though initially believed to primarily be a respiratory pathogen, the SARS-CoV-2 virus has manifested as a virus that has the potential to affect multiple organ systems causing a wide variety of disease and symptomatology. Case Presentation Here we present a teenager with acute COVID-19 who presented to the hospital with severe rhabdomyolysis causing life-threatening hyperkalemia and acute kidney injury requiring treatment with emergent renal replacement therapy in the intensive care unit. Conclusions Rhabdomyolysis and acute kidney injury are increasingly recognized as complications of acute SARS-CoV-2 infection, and require vigilance given the associated risk of morbidity and mortality.

New predictive biomarkers for screening COVID-19 patients with rhabdomyolysis in combination with cystatin C

“…In our study, the incidence of RM was 3.9%, whereas the incidence of SKM was 15.2, which is slightly higher than previously reported. Although less frequently described in COVID-19 patients, RM is a potentially fatal condition that can result in abrupt renal failure that may be one of the important complications in patients with COVID-19 (36,39–42). Early detection and effective intervention for RM may reduce mortality and improve prognosis in COVID-19 (6,41,43,44).…”

“…In our study, the incidence of RM was 3.9%, whereas the incidence of SKM was 15.2, which is slightly higher than previously reported. Although less frequently described in COVID-19 patients, RM is a potentially fatal condition that can result in abrupt renal failure that may be one of the important complications in patients with COVID-19 (36,(39)(40)(41)(42). Early detection and effective intervention for RM may reduce mortality and improve prognosis in COVID- 19 Geng et al (41) noted that CK and MYO concentration tests need to be taken more seriously and monitored in COVID-19 patients for early RM diagnosis, but there is no suggestion of a specific scope for warning or practical application directions.…”