Covid-19 and spirometry in this age

Klain, Angela; Indolfi, Cristiana; Dinardo, Giulio; Decimo, Fabio; Giudice, Michele Miraglia Del

doi:10.1186/s13052-022-01199-5

Cited by 12 publications

(6 citation statements)

References 11 publications

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“…This is to a study by the COVID-UPO Clinical Team and Sainaghi in Italy, which found a significantly lower P/F ratio in non-survivor patients compared to survivors (246 [184-300] vs 126 [100-202], p< 0.001). [35] From the statistical analysis in this study, it was found that patients who experienced a decrease in the ratio of PaO2/FiO2 increased the risk of mortality by 43.1 times (95% CI 19.461-95.478; p <0.001). This is consistent with a study by Izcovich A, et al of 1887 patients showing an increase in mortality of 20.3% in patients with a low PaO2/FiO2 ratio (odd ratio 21.17, 95% CI 4.9-91.3).…”

Section: Discussionmentioning

confidence: 65%

Comorbid Diseases, Decreased PaO2/FiO2 Ratio, Increased Ferritin, Decreased Liver and Kidney Function as Risk Factors for Mortality in COVID-19 Patients

Latuheru¹,

Ngurah²,

Sajinadiyasa³

et al. 2023

International Journal of Scientific Advances

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Background: Comorbid disease, a ratio of partial pressure of oxygen (PaO2) to a fraction of inspired oxygen (FiO2) (P/F ratio), ferritin serum, liver function, and kidney function correlate with mortality; hence, these factors are suggested as the prognostic markers in COVID -19. This study aims to analyze comorbid diseases, decreased PaO2/FiO2 ratio, increased ferritin, and decreased liver and kidney function as risk factors for mortality in COVID-19 patients. Methods: An analytic observational study with a match case-control design. Analysis was performed univariate, bivariate with the chi-squared test, and multivariate analysis using binary logistic regression analysis. Results: The subjects of the study were 220 people. The comorbid disease and the mortality of COVID-19 patients (p=0.038, OR=2.737, 95% CI 1.020 to 7.342), PaO2/FiO2 ratio to COVID-19 patient mortality (p=0.000, OR=43.1 95% CI 19.461 to 95.478), ferritin serum levels to COVID-19 patient mortality (p=0.000, OR=53.3, 95% CI 21.014 to 135.110), decreased liver function to COVID-19 patient mortality (p=0.000, OR=62.4 95% CI 25.323 to 153.567), decreased kidney function to COVID-19 patient mortality (p=0.000, OR=1389.7 95% CI 170.8 to 11307.2). The most dominant variable related to the death of COVID-19 patients is the decreased kidney function with an OR value of 722.447 (95% CI 33.356 to 15647.243). Conclusion: Risk factors of mortality of COVID-19 patients are comorbid disease, decrease in PaO2/FiO2 ratio, increase in ferritin, decrease in liver function, and decrease in kidney function. Of all these, the most dominant risk factor related to the highest mortality rate among COVID-19 patients is the decrease in kidney function.

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Section: Discussionmentioning

confidence: 65%

Comorbid Diseases, Decreased PaO2/FiO2 Ratio, Increased Ferritin, Decreased Liver and Kidney Function as Risk Factors for Mortality in COVID-19 Patients

Latuheru¹,

Ngurah²,

Sajinadiyasa³

et al. 2023

International Journal of Scientific Advances

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“…The vaccination availability together with the application of safety protocols gives the opportunity not only to prevent infection spread but also to schedule clinical controls as well as diagnostic procedures which may have been postponed in non-urgent cases, such as pulmonary function tests [ 63 , 64 ].…”

Section: Resultsmentioning

confidence: 99%

Year 2022: exploring COVID-19 pandemic in children

Bozzola,

Caffarelli,

Santamaria

et al. 2023

Ital J Pediatr

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COVID-19 pandemics is rapidly changing. In this article, we review progresses published in the Italian Journal of Pediatrics in 2022. More data on clinical pictures, prevention strategies and active management in children have been provided. The continued evolution of knowledge has driven transformations in the clinical approach to the disease and allowed key advancements in the care of children with COVID-19.

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“…Many studies show that allergy and asthma, if under control, did not represent risk factors for the susceptibility to SARS-CoV-2 [43] , [44] , [45] , [46] . The role of spirometry, in the COVID era, still remains fundamental in the diagnosis and follow-up of respiratory diseases, in compliance with current containment measures [47] .…”

Section: Does Vitamin D Deficiency Increase the Risk And Severity Of ...mentioning

confidence: 99%