COVID-19 Aortitis: A Review of Published Cases

Hassan, Falah Abu; Alhalawa, Minas Abu; Majdoubeh, Yacoub; Nepal, Ashish; Sufan, Sareen S

doi:10.7759/cureus.22226

Cited by 6 publications

(5 citation statements)

References 16 publications

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“…Aortitis after COVID-19 has been previously reviewed by Hassan et al [ 11 ], and several cases have been reported since. Seven cases of aortitis secondary to COVID-19, including our case, were included in our review ( Table 2 ) [ 4 , 12 , 13 , 14 , 15 , 16 ].…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Improvement of Aortitis Associated with Severe COVID-19 Infection—A Case Report

et al. 2023

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Aortitis is a rare complication of the coronavirus disease 2019 (COVID-19) and is often treated empirically with steroids. We present a case of spontaneous resolution of aortitis without treatment. A 65-year-old man was admitted to our intensive care unit for severe COVID-19 pneumonia and underwent rehabilitation in the general ward. On day 12, he developed fever, and on day 13, he developed right cervical pain and increased inflammatory markers. On day 16, a cervical echocardiogram showed vasculitis in the right common carotid artery, and on day 17, computed tomography (CT) of the neck showed thickening of the arterial wall of the right common to the internal carotid arteries. A retrospective assessment of the CT scan on day 12 showed wall thickening from the thoracic aorta to the abdominal aorta, and a diagnosis of aortitis was made. Autoantibody analysis, culture, and magnetic resonance imaging (MRI) of the head and neck showed no abnormalities. During the investigation of the cause of aortitis, the fever and inflammatory reaction spontaneously resolved and the right cervical pain gradually improved. Therefore, the patient was diagnosed with transient COVID-19-related aortitis. To our knowledge, this is the first report describing the spontaneous resolution of COVID-19-related aortitis.

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Section: Discussionmentioning

confidence: 99%

Spontaneous Improvement of Aortitis Associated with Severe COVID-19 Infection—A Case Report

et al. 2023

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“…Es wurden bisher zahlreiche Fallberichte veröffentlicht, welche das Auftreten von verschiedensten Immunvermittelten Krankheiten (u. a. Aortitis) nach COVID-19-Infektion beschreiben [36,37,38,39,40,41]. Die Mehrheit der Patienten wies lediglich milde Symptome der Covid-19-Infektion mit Husten, Schnupfen und Fieber auf.…”

Section: Covid-19 Als Trigger Für Vaskulitis Und Aortitisunclassified

Takayasu – Arteriitis nach COVID-19-Infektion bei einer 26 Jahre alten Patientin mit Morbus Crohn

Kollecker,

Nistal,

Waltz

et al. 2024

Z Gastroenterol

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ZusammenfassungExtraintestinale Manifestationen z.B. an Haut, Gelenken oder Leber finden sich bei Morbus Crohn häufig. Wir berichten über eine 26 Jahre alte Patientin mit langjährig bekanntem Morbus Crohn, die bei V.a. erneuten akuten Schub bei suggestiver Klinik und laborchemisch deutlich erhöhten Entzündungswerten stationär aufgenommen wurde. Kurze Zeit vorher war die Diagnose einer symptomatischen COVID-19-Erkrankung (SARS-CoV-2-Variante Omikron) gestellt worden. Mittels umfassender endoskopischer und bildgebender Diagnostik konnte eine aktive Crohn-Erkrankung ausgeschlossen werden. Es zeigte sich jedoch eine langstreckige entzündliche Verdickung des Aortenbogens, sodass die Diagnose einer Takayasu-Arteriitis (Typ II b) gestellt werden konnte. Unter Steroidtherapie kam es zu einer raschen und anhaltenden Besserung der klinischen Symptomatik. Das Auftreten einer Takayasu-Arteriitis ist außerhalb von Japan ausgesprochen selten. Eine Koinzidenz mit chronisch entzündlichen Darmerkrankungen ist beschrieben und wird als mögliche extraintestinale Manifestation diskutiert. Das Auftreten immunvermittelter Erkrankungen nach COVID-19-Erkrankungen ist beschrieben und wird möglicherweise durch die Infektion getriggert. Patienten mit chronisch entzündlichen Darmerkrankungen könnten möglicherweise eine besondere Risikopopulation darstellen.

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“…Streptococcus pneumoniae is one of the predominant pathogens for infective aortitis 5 . SARS-CoV-2 infection has also been implicated in aortitis 6,7 . 18 F-FDG PET shows increased uptake in active infectious aortitis and can be used to monitor inflammatory activity after treatment 8,9 .…”

mentioning

confidence: 99%

Infectious Aortitis on 18F-FDG PET/CT

El Hoyek,

Chen,

Aktay

2024

Clin Nucl Med

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Infectious aortitis is a challenging radiographic diagnosis due to overlapping features with the noninfectious category. We present a case of a 58-year-old woman who tested positive for SARS-CoV-2 and Streptococcus pneumoniae bacteremia. 18F-FDG PET/CT demonstrated large vessel vasculitis involving the thoracic, abdominal aorta, and the brachiocephalic branches of the aortic arch, and an incidental subcutaneous abscess in the right arm. Standard of care treatment was administered. Within a week, a drastic improvement of the wall thickening was noted, which can be, regardless of the biological markers, a surrogate marker of an infectious aortitis.

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COVID-19 Aortitis: A Review of Published Cases

Cited by 6 publications

References 16 publications

Spontaneous Improvement of Aortitis Associated with Severe COVID-19 Infection—A Case Report

Spontaneous Improvement of Aortitis Associated with Severe COVID-19 Infection—A Case Report

Takayasu – Arteriitis nach COVID-19-Infektion bei einer 26 Jahre alten Patientin mit Morbus Crohn

Infectious Aortitis on 18F-FDG PET/CT

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