COVID-19 ARDS in two patients with left ventricular assist device

Özgür, Mustafa; Hançer, Hakan; Altaş, Özge; Kırali, Kaan

doi:10.1007/s10047-021-01288-y

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…Among these reasons: the demographics of the patients (elderly with several comorbidities), abnormal immune system, and a variety of cytokines activation [7]. With the onset of the COVID-19 pandemic, cases of acute SARS-CoV-2 infection have been reported in LVAD implants [8][9][10][11][12][13][14][15][16][17][18][19][20][21]. In one series of 28 LVAD implants with confirmed COVID-19, 79% were male with median age 65 years, and the majority (82%) were destination therapy (11).…”

Section: Outcomes Of Lvad Patients With Covid-19mentioning

confidence: 99%

Management of Patients with Left Ventricular Assist Device during the COVID-19 Pandemic

2022

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The novel coronavirus disease 2019 (COVID-19) is an infectious disease with multi-organ involvement, including the cardiovascular system. The disease may cause several cardiovascular complications, and may increase morbidity and mortality among patients with background cardiovascular disease. Patients with advanced heart failure are often treated with left ventricular assist device (LVAD), and represent a unique population mandating multi-disciplinary approach. Several aspects of COVID-19 should be taken into account in LVAD implants, including right ventricular involvement, hemodynamic alterations, thromboembolic and haemorrhagic complications, and the psychological effects of social isolation. Patients with VAD and suspected COVID-19 should be transferred to specialized centers for better management of complications. Here, we review the implications of COVID-19 pandemic on LVAD patients with our recommendations for appropriate management.

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Section: Outcomes Of Lvad Patients With Covid-19mentioning

confidence: 99%

Management of Patients with Left Ventricular Assist Device during the COVID-19 Pandemic

2022

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Coronavirus disease 2019 and mechanical circulatory support devices: A comprehensive review

John¹,

Mishra

Nayar

et al. 2022

Monaldi Arch Chest Dis

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Coronavirus disease (COVID-19) can cause circulatory shock refractory to medical therapy. Such patients can be managed with mechanical circulatory support (MCS) devices like IABP, Impella, VA ECMO, and Left Ventricular Assist Devices (LVADs). Moreover, patients on long-term durable LVADs are a special population having increased susceptibility and mortality to COVID-19 infection. In this narrative review, we searched PubMed and Medline for studies on COVID-19 patients on short-term MCS devices. We found 36 papers with 110 patients who met our review criteria, including 89 LVAD patients and 21 COVID-19 patients who needed MCS device therapy. These studies were used to extract patient demographics, clinical presentation, MCS device details, management, and outcomes. Mean age of patients with COVID-19 infection on LVADs was 60, 73% were male, and HeartMate 3 was the most common device (53%). Most patients (77.5%) needed hospitalization, and mortality was 23.6%. Among the 21 reported cases of critically ill COVID-19 patients who required MCS, the mean age was 49.8 years, 52% were women, and the most common MCS device used was VA ECMO (62%) in conjunction with an Impella for LV venting. Comorbidities were not present in 43%, but 71% had abnormal ventricular function on echocardiography. MCS is a viable option for managing severe COVID-19 infection with shock, with many reported cases of favorable outcomes.

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COVID-19 ARDS in two patients with left ventricular assist device

Cited by 2 publications

References 13 publications

Management of Patients with Left Ventricular Assist Device during the COVID-19 Pandemic

Management of Patients with Left Ventricular Assist Device during the COVID-19 Pandemic

Coronavirus disease 2019 and mechanical circulatory support devices: A comprehensive review

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