COVID‐19 cardiac involvement in a 38‐day old infant

Barba, Paolo Del; Canarutto, Daniele; Sala, Elisa; Frontino, Giulio; Guarneri, Maria Pia; Camesasca, C.; Baldoli, Cristina; Esposito, Antonio; Barera, Graziano

doi:10.1002/ppul.24895

Cited by 11 publications

(14 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The characteristics and demographic features of the total of 45 COVID-19 patients with CI included in the selected case reports and case series are demonstrated in supplementary table 3 [ [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] ]. Patients' age ranged from 38 days to 74 years and approximately 62% of them were males.…”

Section: Resultsmentioning

confidence: 99%

“…Case reports/series gave a better insight into the associated factors with CI in each individual. In this review, 11 case studies showed that 78% of COVID-19 patients with CI, were children/adolescentshad none of them had any underlying CVD [ 20 , 21 , [23] , [24] , [25] , [26] , [27] , 30 , [32] , [33] , [34] ]. Furthermore, 50% of the adult COVID-19 patients who developed CI did not have any comorbid CVD.…”

Section: Discussionmentioning

confidence: 99%

“…The patients who died developed further complications such as ST elevation, myocardial infraction, arrhythmias [ 28 ], suspected myopericarditis with ventricular dysfunction [ 29 ], severe necrotizing myocarditis and cardiogenic shock [ 35 ], as well as fulminant myocarditis with MODs 40. However, the two other patients who developed cardiomyopathy, cardiogenic shock [ 23 ], and pericardial effusion [ 31 ] secondary to myocarditis have recovered. One patient had Takostubo [ 36 ] syndrome and three developed other types of CI such as intramural hemorrhage [ 37 ], decompensated heart failure with reduced ejection fraction (HfrEF), atrial dysrhythmias [ 38 ] and decreased ejection fraction with left arterial enlargement [ 39 ], all of which have recovered.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Systemic Inflammation May Induce Cardiac Injury in COVID-19 Patients Including Children and Adolescents Without Underlying Cardiovascular Diseases: A Systematic Review

Aldien¹,

Ganesan²,

Wahbeh³

et al. 2022

Cardiovascular Revascularization Medicine

View full text Add to dashboard Cite

Coronavirus disease 2019(COVID-19) is an ongoing global pandemic with a daily increasing number of affected individuals and a relatively high mortality rate. COVID-19 patients that develop cardiac injury are at increased risk of a worse clinical course with higher rates of mortality. Increasing amounts of evidence suggest that a system-wide inflammatory response and a cytokine storm mediated type syndrome plays a crucial role in disease progression. This systematic review investigates the possible role of hyperinflammation in inducing cardiac injury as one of the severe complications of COVID-19. A systematic literature search was performed using PubMed, Embase and Scopus databases to identify relevant clinical studies that investigatedc ardiovascular injury manifestations and reported inflammatory and cardiac biomarkers in COVID-19 patients. Only 29 studies met our inclusion criteria and the majority of these studies demonstrated significantly elevated inflammatory and cardiac blood markers. It was evident that underlying cardiovascular diseases may increase the risk of developing cardiac injury. However, many COVID-19 patients included in this review, developed different types of cardiac injury without having any underlying cardiovascular diseases. Furthermore, many of these patients were either children or adolescents. Therefore, age and comorbidities may not always be the two main risk factors that dictate the severity and outcome of COVID-19. Further investigations are required to understand the underlying mechanisms of pathogenicity as an urgent requirement to develop the appropriate treatment and prevention strategies. These strategies may specifically target hyperinflammation as a suspected driving factor forsome of the severe complications of COVID-19.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Systemic Inflammation May Induce Cardiac Injury in COVID-19 Patients Including Children and Adolescents Without Underlying Cardiovascular Diseases: A Systematic Review

Aldien¹,

Ganesan²,

Wahbeh³

et al. 2022

Cardiovascular Revascularization Medicine

View full text Add to dashboard Cite

show abstract

“…12 The infant was asymptomatic and there were no complications at birth. 62,63,[80][81][82][83][84][85][86][87] Negative cases 4,68,79,81,88-103 Mix-feeding 3 7 10 Positive cases [104][105][106] Negative cases 107 Not reported feeding practice 76 596 672 Positive cases 63,67, Negative cases 5,10,47,75,111,114,119,120,122, Positive cases 83,193,199,200 Mix-feeding 3 0 3 Positive cases 193,201 Not reported e feeding practice 125 2 127…”

Section: Participantsmentioning

confidence: 99%

Transmission of SARS‐CoV‐2 through breast milk and breastfeeding: a living systematic review

Centeno‐Tablante

Medina‐Rivera

Finkelstein

et al. 2020

Annals of the New York Academy of Sciences

148

123

View full text Add to dashboard Cite

The pandemic of coronavirus disease 2019 (COVID-19) is caused by infection with a novel coronavirus strain, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At present, there is limited information on potential transmission of the infection from mother to child, particularly through breast milk and breastfeeding. Here, we provide a living systematic review to capture information that might necessitate changes in the guidance on breast milk and breastfeeding given the uncertainty in this area. Our search retrieved 19,414 total records; 605 were considered for full-text eligibility and no ongoing trials were identified. Our review includes 340 records, 37 with breast milk samples and 303 without. The 37 articles with analyzed breast milk samples reported on 77 mothers who were breastfeeding their children; among them, 19 of 77 children were confirmed COVID-19 cases based on RT-PCR assays, including 14 neonates and five older infants. Nine of the 68 analyzed breast milk samples from mothers with COVID-19 were positive for SARS-CoV-2 RNA; of the exposed infants, four were positive and two were negative for COVID-19. Currently, there is no evidence of SARS-CoV-2 transmission through breast milk. Studies are needed with longer follow-up periods that collect data on infant feeding practices and on viral presence in breast milk.

show abstract

“…Daniele Canarutto MD 1,2,3 Paolo Del Barba MD 1 Marianna Di Frenna MD 1 Federica Del Tedesco MD 1,2 Roberta Pajno MD 1 Maria Pia Guarneri MD 1 Graziano Barera MD 1,2 1…”

Section: Prolonged Asymptomatic Sars-cov-2 Infection In a Child Receimentioning

confidence: 99%

Prolonged asymptomatic SARS‐CoV‐2 infection in a child receiving immunosuppressive therapy

Canarutto

Barba

Frenna

et al. 2020

Pediatric Pulmonology

Self Cite

View full text Add to dashboard Cite

COVID‐19 cardiac involvement in a 38‐day old infant

Cited by 11 publications

References 6 publications

Systemic Inflammation May Induce Cardiac Injury in COVID-19 Patients Including Children and Adolescents Without Underlying Cardiovascular Diseases: A Systematic Review

Systemic Inflammation May Induce Cardiac Injury in COVID-19 Patients Including Children and Adolescents Without Underlying Cardiovascular Diseases: A Systematic Review

Transmission of SARS‐CoV‐2 through breast milk and breastfeeding: a living systematic review

Prolonged asymptomatic SARS‐CoV‐2 infection in a child receiving immunosuppressive therapy

Contact Info

Product

Resources

About