COVID-19: Clinical, Immunological, and Image Findings from Infection to Post-COVID Syndrome

Abstract

The SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) is a virus responsible for the COVID-19 pandemic outbreak. The virus has high infectious power and easy ability to spread geographically, due to the fact that the infection is asymptomatic in some cases. However, 25% of patients infected by SARS-CoV-2 can progress to the severity of the disease and develop acute respiratory distress syndrome (ARDS). The symptoms are commonly recognized as fever, dry cough, tachypnea, shortness of breath, sore throat, sneezing, nasal congestion, and other symptoms, including severe inflammatory responses with the evolution of cytokine storm, pneumonia, and sepsis. Here, we show the COVID-19 since infection in the host cell to Post-COVID-19 syndrome, relating the occurrence of virus variants, laboratory and immunological aspects, the major clinical manifestations and image findings, and all aspects associated with pulmonary damage promoted by the virus.