COVID-19 complicated by infective endocarditis or concomitant infection? a case report

Abstract

Coronavirus disease 2019 (COVID-19) is a global pandemic and public health emergency. With a high infectivity and dissemination rate, cardiovascular complications have been observed and associated with a poorer prognosis. COVID-19 appears to be both a risk and prognosis factor for infective endocarditis. In this report, we present the case of a 53-year-old woman with a non-productive cough, progressive dyspnea and fatigue, diagnosed with COVID-19 four weeks earlier. The patient was referred to our department displaying the same symptoms. She was diagnosed with infective endocarditis of the mitral valve based on clinical symptoms, as well as radiological and analytical investigations. The patient was given appropriate medical treatment before admission based on azithromycin, corticosteroids for two weeks, during the hospitalization, she underwent treatment with antibiotics based on Teicoplanin and gentamicin. Outcome was good; the disappearance of the vegetative lesion on the weekly transthoracic echocardiogram (TTE). This rare case highlights questions about considering other coexisting diagnoses as well as possible complications a long with COVID-19.

A Comprehensive Review on Cardiovascular Complications of COVID-19: Unraveling the Link to Bacterial Endocarditis

“…The potential interplay between COVID-19 and bacterial endocarditis is a complex dynamic shaped by shared risk factors and underlying conditions that can create a fertile environment for both viral infection and bacterial colonization to occur. Gaining a deeper understanding of these factors can illuminate the intricate relationship between the two entities [ 44 ].…”

Cardiovascular complications and predictors of mortality in hospitalized patients with COVID-19: a cross-sectional study from the Indian subcontinent

“…We enrolled patients in our study at the beginning of the pandemic in our country, so they were exposed to COVID-19 for the first time with no prior exposure [ 1 ]. The case report published by Miri et al [ 3 ] has clearly mentioned that the patient had COVID-19 1 month prior and recent RT-PCR was negative during the second admission with infective endocarditis. The second case reported by Romeo et al [ 4 ] had a history of prior cardiac surgery, and he was treated with corticosteroids, long broad-spectrum antibiotics, and immunosuppressors during his prolonged ICU stay with COVID-19 illness; he was later readmitted with a fungal infection.…”

“…Their fourth concern was that endocarditis was not mentioned as a cardiac complication of COVID-19, which had recently been reported in a few case reports [3][4][5]. However, patients with preexisting cardiac conditions, including prosthetic valves and implanted devices, were already excluded from our study [1].…”

Anais do Congresso Médico Acadêmico da Escola Superior de Ciências da Saúde

“…Nos últimos anos, vários são os impactos que a pandemia da COVID-19 tem acarretado na sociedade, afetando desde os relacionamentos interpessoais à saúde dos indivíduos. Assim, se no seu auge a pandemia levou ao sobrecarregamento do sistema de saúde pelo surgimento de uma demanda hospitalar sem precedentes, hodiernamente, se estuda sua repercussão no sistema de saúde decorrente de sua correlação com o desenvolvimento secundário de outras patologias, como a endocardite infecciosa (EI), uma infecção que acomete o coração, em especial as válvulas e a superfície endocárdica, prejudicando o seu funcionamento correto (MIRI C, et al, 2022).…”