COVID-19 impact on hematological and biochemical parameters on outcomes of admitted patients

Abstract

COVID-19 an ongoing pandemic has high transmission and mortality rate gets the attention of researchers to focus on the disease. The burden of disease on the health care system focuses on the COVID-19 impacts on the hematological and biochemical parameters. This study aimed to focus on the laboratory indicators that fluctuate in COVID-19. The single-center cross-sectional study in the pathology department of POF hospital Wah Cantt from August 2021 to December 2021. Three hundred positive COVID-19 patients were included in the study. About 138 (46%) were males and 162 (54%) females and the mean age was 58 ± 15.06 (range 5 – 86). The biochemical indicator raised in COVID-19 included CPK (191.25 ± 507.39), CRP (68.81 ± 70.95), LDH (429.48 ± 246.96), and ALT (46.50 ± 43.23). In hematological parameters, only neutrophils elevated (70.00 ± 13.52) lymphocytes decreased. Laboratory parameters measured were similar values in recovered and death cases. The findings suggest the raised level of CRP, LDH, CPK, ALT, ferritin, D-Dimer, and neutrophils predict early diagnosis and prompt treatment.