COVID-19 in Light of Seasonal Respiratory Infections

Kiseleva, Irina; Grigorieva, Elena; Larionova, Natalie; Farroukh, Mohammad Al; Rudenko, Larisa

doi:10.3390/biology9090240

Cited by 8 publications

(4 citation statements)

References 93 publications

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“…The virus responsible for COVID-19 was first detected in Wuhan, China, in late 2019 [1] and was declared a global health emergency by the World Health Organization (WHO) in January 2020 [2]. The virus is primarily responsible for human and animal respiratory infections, with high morbidity and mortality rates that have negatively impacted the economic development of many countries [3][4][5]. Worldwide, there have been 753 million reported COVID-19 cases and more than 6.8 million deaths in February 2023 [6].…”

Section: Introductionmentioning

confidence: 99%

Seroprevalence of SARS‐CoV‐2 Antibodies and Associated Factors in Bamako, Mali: A Population‐Based Cross‐Sectional Study in September 2022

Traoré,

Guindo,

Konaté

et al. 2024

Influenza Resp Viruses

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BackgroundThe sero‐epidemiological characteristics of SARS‐CoV‐2 infections in Mali are not yet well understood. This study assessed SARS‐CoV‐2 antibody seroprevalence and factors associated with antibody responses in the general population of Bamako, the capital city and epicenter of COVID‐19, to assess the magnitude of the pandemic and contribute to control strategy improvements in Mali.MethodsA cross‐sectional survey was conducted in September 2022 to collect sociodemographic information, clinical characteristics, comorbid factors, and blood samples. ELISA was performed to determine anti‐Spike (anti‐S) and anti‐RBD antibody levels. A total of 3601 participants were enrolled in REDCap. R‐Studio was used for the statistical analysis. The chi‐squared (χ2) test was used to compare the proportions across different groups. Logistic regression models were used to elucidate factors associated with antibody responses.ResultThe sex ratio for female‐to‐male was 3.6:1. The most representative groups were the 20–29‐year‐olds (28.9%, n = 1043) and the 30–39‐year‐olds (26.9%, n = 967). The COVID‐19 vaccine coverage among the participants was 35.8%, with vaccines from Covishield AstraZeneca (13.4%), Johnson & Johnson (16.7%), Sinovac (3.9%), and BioNTech Pfizer (1.8%). Overall, S protein and RBD antibody seroprevalences were remarkably high in the study population (98% and 97%, respectively). Factors such as youth (1–9 years old) and male sex were associated with lower SARS‐CoV‐2 antibody responses, whereas COVID‐19 vaccinations were associated with increased antibody responses.ConclusionThis serosurvey demonstrated the high seroprevalence of SARS‐CoV‐2 antibodies and highlighted the factors influencing antibody responses, while clearly underlining an underestimation of the pandemic in Mali.

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Section: Introductionmentioning

confidence: 99%

Seroprevalence of SARS‐CoV‐2 Antibodies and Associated Factors in Bamako, Mali: A Population‐Based Cross‐Sectional Study in September 2022

Traoré,

Guindo,

Konaté

et al. 2024

Influenza Resp Viruses

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“…At the beginning of the spread of SARS-CoV-2 around the world, it was suggested that the pandemic would likely develop in accordance with one of two scenarios: (i) SARS-CoV-2 viruses would co-circulate with other viral respiratory pathogens, or (ii) SARS-CoV-2 viruses would displace them [ 8 ]. However, as the pandemic developed, it became clear that a third, combined scenario might have taken place.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Shuts Doors to Flu but Keeps Them Open to Rhinoviruses

Kiseleva

Ksenafontov

2021

Biology

Self Cite

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It is well known that rhinoviruses are distributed across the globe and are the most common cause of the common cold in all age groups. Rhinoviruses are widely considered to be harmless because they are generally perceived as respiratory viruses only capable of causing mild disease. However, they may also infect the lower respiratory tract, inducing chronic obstructive pulmonary disease and exacerbations of asthma, bronchiolitis, etc. The role of rhinoviruses in pathogenesis and the epidemiological process is underestimated, and they need to be intensively studied. In the light of recent data, it is now known that rhinoviruses could be one of the key epidemiological barriers that may influence the spread of influenza and novel coronaviruses. It has been reported that endemic human rhinoviruses delayed the development of the H1N1pdm09 influenza pandemic through viral interference. Moreover, human rhinoviruses have been suggested to block SARS-CoV-2 replication in the airways by triggering an interferon response. In this review, we summarized the main biological characteristics of genetically distinct viruses such as rhinoviruses, influenza viruses, and SARS-CoV-2 in an attempt to illuminate their main discrepancies and similarities. We hope that this comparative analysis will help us to better understand in which direction research in this area should move.

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“…As winter settles down in the Northern hemisphere, the current SARS-CoV-2 pandemic has generated preoccupation since it, very likely, will cocirculate with other respiratory infections, particularly influenza and RSV [20, 21, 22, 23, 24], although interactions with other respiratory disease are certainly possible [25].…”

Section: Introductionmentioning

confidence: 99%

Co-circulation of two viral populations under vaccination

Acuña-Zegarra

Núñez-López

Comas‐García

et al. 2021

Preprint

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The interaction and possibly interference between viruses infecting a common host population is the problem addressed in this work. We model two viral diseases both of the SIRS type that have similar mechanism of transmission and for which a vaccine exists. The vaccine is characterized by its coverage, induced temporal immunity and efficacy. The population dynamics of both diseases considers infected individuals of each disease and hosts that are susceptible to one but have recovered from the other. We do not incorporate coinfection. We postulate two main transmission factors affecting the effective contact rates: i) that the virus with higher reproduction number can superinfect the one with lower reproduction number and ii) that there is some protection induced by vaccination against the weaker virus that reduces the probability of infection by the stronger virus. Our results indicate that coexistence of the viruses is possible in the long term. The time-dependent effective contact rate may induce either alternating outbreaks of each disease or synchronous outbreaks. We also found the existence of bi-stability triggered by a backward bifurcation, conducive to scenarios where, at the population level, vaccine application may promote persistence of both diseases provided the effective coverage and vaccine efficacy are low.

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COVID-19 in Light of Seasonal Respiratory Infections

Cited by 8 publications

References 93 publications

Seroprevalence of SARS‐CoV‐2 Antibodies and Associated Factors in Bamako, Mali: A Population‐Based Cross‐Sectional Study in September 2022

Seroprevalence of SARS‐CoV‐2 Antibodies and Associated Factors in Bamako, Mali: A Population‐Based Cross‐Sectional Study in September 2022

COVID-19 Shuts Doors to Flu but Keeps Them Open to Rhinoviruses

Co-circulation of two viral populations under vaccination

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