COVID-19 in Neonates with Positive RT–PCR Test. Systematic Review

García, Heladia; Allende-López, Aldo; Morales-Ruíz, Paulina; Miranda-Novales, Guadalupe; Villasís-Keever, Miguel Ángel

doi:10.1016/j.arcmed.2022.03.001

Cited by 18 publications

(33 citation statements)

References 100 publications

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“…Studies show that most newborns infected with SARS-CoV-2 remain asymptomatic or develop a moderate form of the disease [ 31 , 32 ]. In our case, two newborns had an unremarkable physical examination, and one patient presented mild respiratory distress syndrome, which may be linked to COVID-19 infection.…”

Section: Discussionmentioning

confidence: 99%

“…They highlight the importance of a follow-up with newborns [ 38 ]. Monitoring cases of disease with persistent symptoms and the newborn’s development, highlighting possible sequelae that appear later in life are essential [ 31 , 39 ]. Therefore, the mothers included in this presentation received, at the discharge, the recommendation to consult the family doctor to record and monitor the subsequent evolution of the newborns [ 39 ].…”

Section: Discussionmentioning

confidence: 99%

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First Neonates with Vertical Transmission of SARS-CoV-2 Infection in Late Pregnancy in West Part of Romania: Case Series

et al. 2022

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The Coronavirus disease 2019 (COVID-19) pandemic has exposed the vulnerable neonatal population to unknown risks. Given that herd immunity is has not been reached, the entire population is susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 Virus(SARS-CoV-2) infection. The arising concern about the vertical transmission of neonatal complications caused by the novel coronavirus is a continuous challenge for managing newborns, considering the rare cases and unclear guidelines. Therefore, a retrospective study was conducted in a tertiary unit from Timisoara, Romania. Of the 283 newborns born during the study period, only 3 neonates were diagnosed with SARS-CoV-2 infection in the first 24 h of life (DOL-0). The present study plans to identify the findings, including clinical features, laboratory characteristics, and outcomes of newborns with vertical transmission of SARS-CoV-2. All infected neonates were confirmed with COVID-19 by Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) from nasal aspirates and were isolated in the neonatology department. They were the first and the only neonate infected at birth from the West part of Romania. The clinical findings were unremarkable except for one neonate who developed mild respiratory distress syndrome. Elevated IgG-specific anti-SARS-CoV-2 serum levels were found in one newborn. Swab samples in DOL-0 strengthened the awareness of vertical transmission, although peripartum SARS-CoV-2 infection does not seem responsible for severe symptoms. We conclude that vertical transmission is rare in late pregnancy. Even if the studied newborns showed mild forms of COVID-19, it is essential to note that newborns represent a particular category of patients. More studies are needed to complete the observations of this study.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

First Neonates with Vertical Transmission of SARS-CoV-2 Infection in Late Pregnancy in West Part of Romania: Case Series

et al. 2022

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“…Neonates to SARS-CoV-2 positive pregnancies may be asymptomatic or have mild to moderate symptoms. The most described symptoms are lethargy, irritability, hypotonia, poor feeding, diarrhoea, vomiting, cough, rhinorrhoea, fever, tachycardia, tachypnoea and respiratory distress [152] . The most described symptoms are lethargy, irritability, hypertonia, poor feeding, cough, fever, tachypnoea, and pneumonia.…”

Section: The Placenta Fetus and Neonatementioning

confidence: 99%

Functional consequences of SARS-CoV-2 infection in pregnant women, fetoplacental unit, and neonate

Carvajal

Casanello

Farías

et al. 2023

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Diseas

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“…The outbreak has therefore begun to enable diagnostic assays for screening and preventing the spread of the disease. Current diagnostic methods have solely relied on the nucleic acid amplification technologies, such as real time - polymerase chain reaction (RT-PCR) [ [4] , [5] , [6] ] and Loop mediated isothermal amplification (LAMP) [ [7] , [8] , [9] ]. Nevertheless, these methods have merits, such as they require expensive instruments and sophisticated operation steps which are the key bottlenecks in testing that dramatically increases cost and assay time from sample-to-answer.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2

Jaewjaroenwattana

Phoolcharoen

Pasomsub

et al. 2023

Talanta

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COVID-19 in Neonates with Positive RT–PCR Test. Systematic Review

Cited by 18 publications

References 100 publications

First Neonates with Vertical Transmission of SARS-CoV-2 Infection in Late Pregnancy in West Part of Romania: Case Series

First Neonates with Vertical Transmission of SARS-CoV-2 Infection in Late Pregnancy in West Part of Romania: Case Series

Functional consequences of SARS-CoV-2 infection in pregnant women, fetoplacental unit, and neonate

Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2

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