“…A recently published paper based on the National COVID Cohort Collaborative electronic health record data showed that severe outcomes of Covid-19 infection were not greater in the NF1 cohort than in other disease cohorts. 12 However, there is still a lack of validated research data to support the vaccination of NF1 patients, which leaves patients’ concerns unaddressed. Based on our analysis of the common symptoms and changes in the condition of NF1 patients after Covid-19 infection and vaccination, we found that the most common symptoms of NF1 patients after infection were fever and cough, which were consistent with the general population and did not differ significantly in incidence.…”