Background: This study assessed health literacy (HL) and its associated factors among older adults during the coronavirus disease 2019 (COVID-19) pandemic.Methods: This cross-sectional study included older adults in urban communities in Thailand. We randomly selected a total of 421 older adults and performed multiple logistic regression analyses.Results: The average age of the respondents was 70.0±7.1 years. Most respondents were female, married, had a low education level (primary school or lower), were unemployed, and had sufficient income. We observed nonproficient and proficient HL levels in 56.1% and 43.9% of respondents, respectively. The factors influencing HL included attending healthcare services at a tertiary hospital, good accessibility to COVID-19 prevention materials and health information, and provision of a high level of social support from neighbors and health personnel.Conclusion: The results of our study provide important information on the outcome of accessibility and social support among older adults in an urban community during the COVID-19 pandemic. In addition, access to health services, prevention equipment, and information was important for people at risk of HL and helped promote good behaviors.