COVID-19 Infection and Acute Kidney Injury: About 43 Cases Report Collected at the Nephrology Department of the Farah Polyclinic in Abidjan

Abstract

Background: Acute kidney injury (AKI) is one of the increasingly described complications of coronavirus infection. Objectives: To identify factors associated with death in patients with acute kidney injury (AKI) during Coronavirus disease (COVID-19) in Abidjan, Côte d'Ivoire. Material and Method: This was a monocentric retrospective analytical study of all patients over 18 years of age with AKI during COVID-19 at the Farah Polyclinic in Abidjan, Côte d'Ivoire. AKI was defined and ranked according to Kidney Disease Improving Global Outcomes (KDIGO) 2012. The data were collected from the medical record and processed using RStudio. Results: Forty-three cases were collected. The average age was 58.5 12 years. The sex ratio (M/F) was 4.4. The main comorbidities were high blood pressure (60.4%) and diabetes (37.2%). AKI was at KDIGO stage 3 in 58%, KDIGO 2 in 21% and KDIGO 1 in 21%. The diagnosis of acute tubular necrosis was retained in 44.2% of patients followed by acute functional kidney injury in 32.6%. Hemodialysis was initiated in 48.8% of cases. The main indication of dialysis was anuria (46.6%). In total, 55.8% of patients died. Factors associated with death were KDIGO stage (p = 0.049), and invasive ventilation (p < 0.001) associated with the risk of death in univariate analysis. Conclusion: Mortality is high in patients with AKI during COVID-19 infection.

Kidney dysfunction and mortality risk in hospitalized Covid-19 patients: A large Covid-19 centre experience

“…(10) In SSA and specifically reporting on AKI as the dysfunction, Ibrahim et al reported AKI occurring in 14.6% of their patients while Dolaamas reported higher in 32.6% . (20,21) A report from a hospital-based registry in Ghana showed that 10% of patients admitted with COVID-19 had underlying CKD with AKI in nearly half of the cases. (22) This wide variation in prevalence of the kidney abnormalities is most likely due to heterogeneity in cohorts studied, from variations in definitions and components of kidney dysfunction to methods employed in diagnosis and reporting.…”