COVID-19 infection and vaccination rates in healthcare workers in British Columbia, Canada: A Longitudinal Urban versus Rural Analysis of the Impact of the Vaccine Mandate

Yassi, Annalee; Barker, Stephen; Lockhart, Karen; Taylor, Deanne; Harris, Devin; Hundal, Harsh; Grant, Jennifer; Okpani, Arnold Ikedichi; Pollock, Sue; Sprague, Stacy; Sing, Chad Kim

doi:10.1101/2022.01.13.22269078

Cited by 4 publications

(5 citation statements)

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“…EMA recommendations on extra doses and boosters were published 4 October 2021, thus the analysis of antibody levels after booster doses was not included in the study ( 12 ). Based on data acquired from the European Center for Disease Prevention and Control website, regional public health agencies, and other studies, this rate was similar to the median value – 88% - of the vaccination rates of EU/EEA countries for fully vaccinated ( 13 , 14 ). Compared to individual countries, the HCWs vaccination rates in our study were lower than those of Canada – 92% ( 13 ), and higher than those reported from France – 71% ( 15 ), United Kingdom – 75% ( 14 ) and United States – 70% ( 16 ) It should be noted that up until March 1, 2022, vaccinations were not mandatory for HCWs in Poland.…”

Section: Discussionsupporting

confidence: 70%

“…Based on data acquired from the European Center for Disease Prevention and Control website, regional public health agencies, and other studies, this rate was similar to the median value – 88% - of the vaccination rates of EU/EEA countries for fully vaccinated ( 13 , 14 ). Compared to individual countries, the HCWs vaccination rates in our study were lower than those of Canada – 92% ( 13 ), and higher than those reported from France – 71% ( 15 ), United Kingdom – 75% ( 14 ) and United States – 70% ( 16 ) It should be noted that up until March 1, 2022, vaccinations were not mandatory for HCWs in Poland. These results show that vaccine hesitancy was not widespread among HCWs in this particular hospital, unlike among other Poles – in December 2022 less than 60% of the Polish population were fully vaccinated ( 17 , 18 ).…”

Section: Discussionsupporting

confidence: 70%

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SARS-CoV-2 antibody response after mRNA vaccination in healthcare workers with and without previous COVID-19, a follow-up study from the University Hospital in Krakow, Poland

et al. 2023

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IntroductionHealthcare workers (HCWs) from the beginning of the pandemic have been at risk of exposure to SARS-CoV-2, so they were vaccinated as first.ObjectivesThe purpose of the study was to determine the level of antibodies against SARS-CoV-2 in HCWs before and after vaccination with mRNA preparations according to previous COVID- 19.Patients and methodsThe HCWs from the University Hospital in Krakow completed two surveys: the baseline survey before receiving the first dose of vaccine (in January 2021) and the follow-up survey in June 2021. In parallel, two blood samples were collected from each participant at baseline and at follow-up. Total anti-SARS-CoV-2 antibody levels were measured using the ECLIA technique.ResultsAt baseline, 41.1% of HCWs had positive antibody test results, and at follow-up, the vaccinated HCWs had almost 100 times higher antibody levels than the unvaccinated HCWs. Participants under 30 years of age had significantly higher antibody levels in June than older HCWs. Among participants with positive antibody test results in January, HCWs who had experienced asymptomatic COVID-19 had more than five times higher antibody levels in June than HCWs self-reported severe COVID-19. In total, 86.9% of HCWs received Comirnaty or Spikevax. The incidence rate of COVID-19 in the unvaccinated vs. vaccinated group was 13 times higher, 20.5% and 1.9% respectively.ConclusionsThese results confirm the effectiveness of vaccination in the prevention of COVID-19 in HCWs. It is worth getting vaccinated regardless of previous infection. Furthermore, vaccination among HCWs under 30 years of age induced more effective antibody production compared to older individuals.

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Section: Discussionsupporting

confidence: 70%

Section: Discussionsupporting

confidence: 70%

SARS-CoV-2 antibody response after mRNA vaccination in healthcare workers with and without previous COVID-19, a follow-up study from the University Hospital in Krakow, Poland

et al. 2023

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“…The available literature cited above suggests that COVID-19 vaccination coverage varies considerably according to geography, socioeconomic conditions, gender, class, rural-urban divide, the extent of vaccine hesitancy, and access to digital tools such as the internet or social media [ 10 , 11 ]. However, there is a dearth of studies in India that can establish causal impacts between COVID-19 vaccine coverage and covariates such as vaccine hesitancy, geography, education attainment, socioeconomic status, and access to digital tools.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Vaccine Hesitancy and Vaccination Coverage in India: An Exploratory Analysis

et al. 2022

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Our paper examines the key determinants of COVID-19 vaccination coverage in India and presents an analytical framework to probe whether vaccine hesitancy, socioeconomic factors and multi-dimensional deprivations (MPI) play a role in determining COVID-19 vaccination uptake. Our exploratory analysis reveals that COVID-19 vaccine hesitancy has a negative and statistically significant impact on COVID-19 vaccination coverage. A percentage increase in vaccine hesitancy can lead to a decline in vaccination coverage by 30 percent. Similarly, an increase in the proportion of people living in multi-dimensional poverty reduces the COVID-19 vaccination coverage. A unit increase in MPI or proportion of people living in acute poverty leads to a mean decline in vaccination coverage by 50 percent. It implies that an increase in socioeconomic deprivation negatively impacts health outcomes, including vaccination coverage. We additionally demonstrated that gender plays a significant role in determining how access to digital technologies such as the internet impacts vaccine coverage and hesitancy. We found that, as males’ access to the internet increases, vaccination coverage also increases. This may be attributed to India’s reliance on digital tools (COWIN, AAROGYA SETU, Imphal, India) to allocate and register for COVID-19 vaccines and the associated digital divide (males have greater digital excess than females). Conversely, females’ access to the internet is statistically significant and inversely associated with coverage. This can be attributed to higher vaccine hesitancy among the female population and lower utilization of health services by females.

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“…Long-term expenditures in healthcare infrastructure and socioeconomic indices are linked to increased use of healthcare services, such as vaccinations. States that have invested much in healthcare and education over the last few decades have well-developed healthcare infrastructure and are better prepared to handle sudden health catastrophes like COVID-19 [16].…”

Section: Discussionmentioning

confidence: 99%

COVID-19 Vaccination and Gaps in India

Choudhary¹,

Choudhary²,

Pervez³

2023

Cureus

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Introduction: The important variables that influence how many people are vaccinated against coronavirus disease in India include vaccine skepticism, socioeconomic status, and multi-dimensional deprivation. Our preliminary research suggests that uncertainty about the safety of the COVID-19 vaccine has a large and detrimental effect on immunization rates.Materials and methods: The Crucial Subsets Survey (CSS) is performed daily on Facebook to recruit participants for cross-section surveys by academic institutions, the Delphi Research Center, and the University of Maryland's Joint Program in Survey Methodology. Facebook will notify a portion of its daily users to take a vote. CSS adds behavior, attitude toward policy and preventive measures, economic consequences, and critical indicators to official reporting data.Results: It has been estimated that a 30% drop in vaccination coverage may be attributed to a 1% rise in vaccine skepticism. Similarly, higher rates of multidimensional poverty are associated with lower rates of COVID-19 vaccine coverage. When the multidimensional poverty index (MPI), or the percentage of persons living in extreme poverty, rises by one unit, immunization rates fall by around half. It suggests that higher rates of socioeconomic hardship have unfavorable effects on health outcomes like vaccination rates. We also showed that gender is a major factor in influencing how internet availability affects vaccination rates and hesitation. We discovered that male vaccination rates went up in tandem with male internet use. This might be because of the digital divide and India's reliance on digital technologies like the COVID Vaccine Intelligence Network (COWIN), AAROGYA SETU, and Imphal, India, to assign and register for COVID-19 vaccinations, while males have greater digital excess than females. While male internet access is significantly and positively correlated with coverage, female internet access is significantly and negatively correlated with coverage. Women are less likely to seek medical care and have more vaccination reluctance than men, both of which contribute to this trend. Conclusion: The government's strategy for disseminating information about the COVID-19 vaccination should prioritize reaching out to women. In order to recruit more women to vaccination clinics, it is important to raise public awareness about the need for immunization among women via the media and community outreach.

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COVID-19 infection and vaccination rates in healthcare workers in British Columbia, Canada: A Longitudinal Urban versus Rural Analysis of the Impact of the Vaccine Mandate

Cited by 4 publications

References 35 publications

SARS-CoV-2 antibody response after mRNA vaccination in healthcare workers with and without previous COVID-19, a follow-up study from the University Hospital in Krakow, Poland

SARS-CoV-2 antibody response after mRNA vaccination in healthcare workers with and without previous COVID-19, a follow-up study from the University Hospital in Krakow, Poland

COVID-19 Vaccine Hesitancy and Vaccination Coverage in India: An Exploratory Analysis

COVID-19 Vaccination and Gaps in India

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