Approximately 600 000 people in the US were anticipated to die of cancer in 2023, 1 and differences in screening, diagnosis, treatment, and mortality vary across health care centers. 2,3 In their cohort study in this issue of JAMA Oncology, Kerekes and colleagues 4 show that immunotherapy is being increasingly initiated in the month before death in the treatment of stage IV cancers, that this practice is more common at nonacademic and lower-volume health care centers, and that such centers have worse 5-year survival rates. This Editorial highlights the strengths and future directions of this research through a health care disparities lens. 2,5,6