COVID-19 Pandemic: Impact on Health Care of Children and the Urgent Need to Restore Regular Healthcare Services

Lodha, Rakesh; Kabra, SK

doi:10.1007/s12098-020-03596-2

Cited by 8 publications

(6 citation statements)

References 9 publications

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“…The region now bears a high burden of dengue with 1.8 billion people living at risk of dengue infection [37]. In addition, all countries in the region also faced the deadly rampage of COVID-19, causing considerable disease burden and socio-economic disruptions [38][39][40][41][42]. Thailand was the first country outside China to identify SARS-CoV-2, probably because it is a popular destination for international tourists, especially from China [39].…”

Section: Clinical Outcomesmentioning

confidence: 99%

Clinical features and outcomes of COVID-19 and dengue co-infection: a systematic review

et al. 2021

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Background Dengue is the most common arboviral disease in the tropical and sub-tropical regions of the world. Like other regions, dengue-endemic areas have faced the additional public health and socio-economic impact of the ongoing coronavirus disease 2019 (COVID-19) pandemic. COVID-19 and dengue co-infections have been reported, with complicated patient management and care requirements. This review aimed to collate and synthesise current knowledge on the clinical features and outcomes of COVID-19 and dengue virus co-infection, a potentially important new dimension to be considered in public health management of the COVID-19 pandemic. Methods A systematic literature review was conducted using PubMed, Web of Science and Scopus databases from 1st January to 21st November 2020. The key search terms used were “dengue” and “coronavirus”. Descriptive analysis with graphical illustrations were used to present the clinical and laboratory parameters of the co-infection. Results Thirteen published papers and four news articles were included in the review. Most studies were case reports with a detailed description of the clinical and laboratory characteristics of the co-infection. All cases were in adults with the exception of a six-year old child. The common symptoms of co-infection were fever, dyspnea, headache, and cough. Common laboratory results included thrombocytopenia, lymphocytopenia, elevated transaminases, and leukopenia. Serious outcomes of co-infection included septic shock, acute respiratory disease syndrome and multi-organ failure, leading to death in some patients. Conclusions COVID-19 and dengue co-infection was associated with severe disease and fatal outcomes. The correct diagnosis and treatment of co-infection poses a substantial challenge due to the overlapping clinical and laboratory parameters. Therefore, confirmative diagnostic tests are necessary for accurate and timely diagnosis and patient management.

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Section: Clinical Outcomesmentioning

confidence: 99%

Clinical features and outcomes of COVID-19 and dengue co-infection: a systematic review

et al. 2021

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“…Dengue became endemic in Asian countries due to trading industry and transportation services in last century due to movement of people [17,18]. Presently, majority of the Asian countries are badly affected with COVID-19 pandemic and resulted in socioeconomic crisis due significant disease burden in compromised health sector [19][20][21][22][23]. India is one of the most affected country due to COVID-19 with ranked second and third in number of affected cumulative cases and deaths, respectively [24].…”

Section: Core Observationsmentioning

confidence: 99%

‘Dengue-COVID-19 overlap’: Is it an ‘antigenic mimicry’ or coexistent two different viral genotypic diseases? Prospective, observational study in tertiary care setting in India

Patil

Bhadake²,

Acharya³

2022

ELECTRON J GEN MED

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Dengue-COVID-19 overlap is mixture of both diseases sharing few similarities in pulmonary and extra pulmonary involvement.Methods: Prospective, observational study, included 300 COVID-19 cases with dengue NS1 or dengue IgM positive, with lung involvement documented and categorized on HRCT thorax at entry point. All cases were subjected to dengue IgG antibody titers and dengue IgM/IgG antibody titer analysis after 12 weeks of discharge form hospital.Results: Hematological evaluation, white blood cell count & platelet count were having significant association with dengue-COVID-19 overlap (p<0.0076) & (p<0.00001), respectively. Clinical parameters as hypoxia have significant association with dengue-COVID-19 overlap (p<0.00001). Inflammatory markers as IL-6, CRP, and LDH has significant association in dengue-COVID-19 overlap (p<0.00001), respectively. Dengue-COVID-19 overlap was documented in 16.33% (49/300) cases. CT severity has documented significant correlation with dengue-COVID-19 overlap cases (p<0.00001). In study of 49 cases of 'dengue-COVID-19', post-COVID-19 lung fibrosis (p<0.004), and serological assessment in dengue IgM/IgG and COVID-19 antibody titers has significant association (p<0.00001). Conclusion:'Dengue-COVID-19' is disease of concern in ongoing pandemic in critical care setting, and timely workup is crucial step in preventing delay in diagnosis and final adverse outcomes.

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“…While some of these could be due to a reduction in seasonal respiratory infections and transmission due to reduced human movement, some of these could be genuine lack of access to transport and reduced non-COVID emergency facilities in under-resourced and low-middle income countries. The reduced number of children presenting to usually busy tertiary respiratory clinics during the pandemic is concerning [ 9 ]. In modelling studies, it has been estimated that the risk of exponential increase in TB cases even with a temporary suspension of TB services could be catastrophic.…”

Section: Effects Of Covid-19 On Children Respiratory Admissions and Health Care Utilizationmentioning

confidence: 99%

“…In modelling studies, it has been estimated that the risk of exponential increase in TB cases even with a temporary suspension of TB services could be catastrophic. Hence, the overall effect of COVID-19 on children can be indirect and complex, and most definitely depends on social and economic factors and these need to be considered carefully [ 9 ].…”

Section: Effects Of Covid-19 On Children Respiratory Admissions and Health Care Utilizationmentioning

confidence: 99%

Asthma Management in the Era of the COVID-19 Pandemic

et al. 2021

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COVID-19 Pandemic: Impact on Health Care of Children and the Urgent Need to Restore Regular Healthcare Services

Cited by 8 publications

References 9 publications

Clinical features and outcomes of COVID-19 and dengue co-infection: a systematic review

Clinical features and outcomes of COVID-19 and dengue co-infection: a systematic review

‘Dengue-COVID-19 overlap’: Is it an ‘antigenic mimicry’ or coexistent two different viral genotypic diseases? Prospective, observational study in tertiary care setting in India

Asthma Management in the Era of the COVID-19 Pandemic

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