COVID-19 pandemic management and the rheumatology patient

Varley, Cara D.; Ku, Jennifer; Winthrop, Kevin

doi:10.1016/j.berh.2021.101663

Cited by 5 publications

(4 citation statements)

References 73 publications

(58 reference statements)

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“…We currently have limited data on vaccine response in this population with one study showing decreased antibody response after a single dose of SARS-CoV-2 mRNA vaccine in those taking methotrexate or rituximab [36]. Given this, we would continue to encourage ongoing public health measures such as mask wearing, social distancing, hand hygiene, and potential vaccination of close contacts given early data showing decreased transmission and viral load following vaccination [39][40][41][42].…”

Section: Discussionmentioning

confidence: 99%

“…As with other vaccines, one should administer SARS-CoV-2 vaccine as far as possible from their last rituximab dose and would avoid rituximab administration for 2-4 weeks after vaccination until more clinical data are available [37,38]. Given this, we would continue to encourage ongoing public health measures such as mask wearing, social distancing, hand hygiene, and potential vaccination of close contacts given early data showing decreased transmission and viral load following vaccination [39][40][41][42].…”

Section: Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2)mentioning

confidence: 99%

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Long-Term Safety of Rituximab (Risks of Viral and Opportunistic Infections)

Varley

Winthrop

2021

Curr Rheumatol Rep

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Purpose of ReviewWe reviewed the current data on infections associated with rituximab use published over the last 5 years. Recent Findings New literature was available on rates of serious infections, Hepatitis B reactivation and screening, and infection with Severe Acute Respiratory Syndrome Coronavirus 2. Summary Rates of infection varied by study and population, however, higher risk of infection in patients with underlying rheumatologic diseases was seen in those who required a therapy switch, had a smoking history, and those undergoing retreatment who had a serious infection with their first course of therapy. With regards to HBV, the proportion of patients screened continues to be inadequate. Despite the upfront cost, HBV screening and prophylaxis were found to be cost effective. There is still limited data regarding COVID-19 severity in the setting of rituximab, however, rituximab, especially in combination with steroids, may lead to more severe disease and higher mortality.

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Section: Discussionmentioning

confidence: 99%

Section: Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2)mentioning

confidence: 99%

Long-Term Safety of Rituximab (Risks of Viral and Opportunistic Infections)

Varley

Winthrop

2021

Curr Rheumatol Rep

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“…For instance, among adolescents with type 1 diabetes, this mode of training was shown to increase physical activity levels and help maintain or improve glycemic control ( 18 , 21 – 23 ). As some chronic conditions (e.g., obesity, immunocompromised diseases) may aggravate COVID-19 prognosis ( 24 , 25 ), forcing home confinement, home-based exercise programs may be a valuable and feasible alternative to maintain or increase physical activity levels ( 23 , 26 ).…”

Section: Discussionmentioning

confidence: 99%

Changes in Eating Habits and Sedentary Behavior During the COVID-19 Pandemic in Adolescents With Chronic Conditions

et al. 2021

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Introduction: Among healthy adolescents, school closures and home confinement were shown to increase unhealthier eating habits and sedentary behavior. It remains unknown to which extent the pandemic has impacted the lifestyle of adolescents with chronic conditions. Thus, the aim of this study is to report on the impact of the COVID-19 outbreak on eating habits and sedentary behavior among adolescents with multiple chronic conditions (n = 347) from a tertiary, referral hospital vs. healthy peers.Methods: This observational study was conducted in São Paulo (Brazil) between July and October 2020, period in which a set of social distancing measures to contain the pandemic.Results: The main findings of this study were that adolescents with chronic conditions and health peers showed important changes in eating habits (e.g., more often cooking and eating in front of television than before quarantine). Also, 86.8% of adolescents with chronic conditions and 91.6% of healthy adolescents reported increasing screen time during pandemic. No major differences were observed between patients and controls.Conclusions: Adolescents with chronic conditions and healthy peers exposed to pandemic showed substantial changes in lifestyle, stressing the need for specific care to mitigate poor eating habits and excessive sedentary behavior for patients and healthy adolescents.

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“…(Bar-Or & Rowland, 2004;Gualano, Bonfa, Pereira, & Silva, 2017) Parents and healthcare providers should encourage physical activities and limit screen time whenever possible, particularly in the context of the pandemic. As some chronic conditions (e.g., obesity, immunosuppressive conditions) may aggravate COVID-19 prognosis, (Richardson, et al, 2020;Varley, Ku, & Winthrop, 2021) forcing home confinement, home-based exercise programs may be a valuable and feasible alternative to maintain or increase physical activity levels. (Schwendinger & Pocecco, 2020) Strengths of this study involve the assessment of a relatively large cohort of patients with several chronic conditions during the most restrictive quarantine in Brazil.…”

Section: Discussionmentioning

confidence: 99%

Changes in eating habits and sedentary behavior during the COVID-19 pandemic in adolescents with chronic conditions

Mazzolani

Smaira

Astley

et al. 2021

Preprint

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Purpose: To report on the impact of the COVID-19 outbreak on eating habits and sedentary behavior among adolescents with multiple chronic conditions (n=347) from a tertiary, referral hospital vs. healthy peers. Methods: This observational study was conducted in Sao Paulo (Brazil) between July and October 2020, period in which a set of social distancing measures to contain the pandemic. Results: The main findings of this study were that adolescents with chronic conditions showed important changes in eating habits (e.g., less often consumption of convenience foods and more often eating in front of television than before quarantine). Also, 86.8% of adolescents with chronic conditions reported increasing screen time during pandemic. No major differences were observed between patients and controls. Conclusions: Adolescents with chronic conditions exposed to pandemic showed substantial changes in lifestyle, stressing the need for specific care to mitigate poor eating habits and excessive sedentary behavior in this group.

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COVID-19 pandemic management and the rheumatology patient

Cited by 5 publications

References 73 publications

Long-Term Safety of Rituximab (Risks of Viral and Opportunistic Infections)

Long-Term Safety of Rituximab (Risks of Viral and Opportunistic Infections)

Changes in Eating Habits and Sedentary Behavior During the COVID-19 Pandemic in Adolescents With Chronic Conditions

Changes in eating habits and sedentary behavior during the COVID-19 pandemic in adolescents with chronic conditions

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