COVID-19 pandemic: The testing times for healthcare workers

Aggarwal, Nitish; Boppana, Tarun Krishna; Mittal, Saurabh

doi:10.4081/monaldi.2021.1515

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…The COVID-19 pandemic originated in Wuhan, China, in December 2019 and subsequently spread worldwide, leading to significant morbidity and mortality [1]. The pandemic has also severely affected India, and healthcare services have been overburdened and disrupted [2,3]. As of November 5, 2020, more than 8 million cases and more than 0.12 million deaths have been reported [4].…”

Section: Introductionmentioning

confidence: 99%

Association of air pollution and coronavirus disease 2019 (COVID-19) in India

Tyagi

Mittal

Madan

et al. 2023

Monaldi Arch Chest Dis

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The COVID-19 pandemic has affected the world, leading to significant morbidity and mortality. Various meteorological parameters are considered essential for the viability and transmission of the virus. Multiple reports from various parts of the world suggest a correlation between the disease spread and air pollution severity. This study was carried out to identify the relationship between meteorological parameters, air pollution, and COVID-19 in New Delhi, one of the worst-affected states in India. We studied air pollution and meteorological parameters in New Delhi, India. We obtained data about COVID-19 occurrence, meteorological parameters, and air pollution indicators from various sources from Apr 1, 2020, till Nov 12, 2020. We performed correlational analysis and employed autoregressive distributed lag models (ARDLM) for identifying the relationship between COVID-19 cases with air pollution and meteorological parameters. We found a significant impact of PM 2.5, PM 10, and meteorological parameters on COVID-19. There was a significant positive correlation between daily COVID-19 cases and COVID-19-related deaths with PM2.5 and PM10 levels. Increasing temperature and windspeed were associated with a reduction in the number of cases while increasing humidity was associated with increased cases. This study demonstrated a significant association of PM2.5 and PM10 with daily COVID-19 cases and COVID-19-related mortality. This knowledge will likely help us prepare well for the future and implement air pollution control measures for other airborne disease epidemics.

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Section: Introductionmentioning

confidence: 99%

Association of air pollution and coronavirus disease 2019 (COVID-19) in India

Tyagi

Mittal

Madan

et al. 2023

Monaldi Arch Chest Dis

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“…Coronavirus disease 2019 (COVID-19) has affected the world over the last year and has led to a significant burden on healthcare systems globally [1]. The disease varies in severity from mild infection to critical illness and is associated with high mortality in patients requiring hospitalization and intensive care unit (ICU) admission.…”

Section: Introductionmentioning

confidence: 99%

Tocilizumab for COVID-19: A systematic review and meta-analysis of randomized controlled trials

Boppana

Mittal

Madan

et al. 2022

Monaldi Arch Chest Dis

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The effective treatment modalities for severe coronavirus disease 2019 (COVID-19) are needed. As the primary cause of mortality is a hyperinflammatory state, the interleukin-6 antagonist tocilizumab has been used in multiple clinical studies. We conducted this systematic review and meta-analysis to estimate the effectiveness of tocilizumab in reduction of mortality due to COVID-19. A systematic search of the Pubmed and Embase databases was performed to extract randomized controlled trials (RCTs) regarding the use of tocilizumab therapy for COVID-19. An overall pooled mortality analysis was performed, and odds ratios were reported. Cochrane risk of bias assessment tool was used to assess the risk of bias. Heterogeneity was assessed using the I2 statistic. Nine RCTs, including 6489 patients, were selected for meta-analysis. Seven trials reported 28-day mortality, and one trial each reported 21-day and 30-day mortality. There were 846 deaths among 3358 participants in the steroid group while 943 deaths among 3131 patients randomized to the control group (random-effects odds ratio 0.87, 95% confidence interval 0.73-1.03, p=0.11). There was some heterogeneity among the trials as the I2 value was 15%, with a p-value of 0.31. There was a reduction in the need for ICU admission in the tocilizumab group. A higher risk of secondary infections was noted in the tocilizumab group (fixed-effects odds ratio 0.72, 95% confidence interval 0.55-0.95, p=0.02). This meta-analysis of RCTs demonstrated that the use of tocilizumab was not associated with a reduction in all-cause mortality in patients with COVID-19 and had higher odds of secondary infections.

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Hygienic aspects of general medicine ward operation: problems and solutions

Pivovarov,

Milushkina,

Kaminer

et al. 2024

Российский Вестник Гигиены

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The existing problems in the field of healthcare and prevention create new challenges and difficulties in various parts of the national public health system. Today, there is an effective set of new sanitary rules and regulations important for competent organization and stable functioning of general medicine wards. In 2023, this set is SanPiN 2.1.3678-20, developed to ensure safe and effective work in medical facilities. There are special bodies tasked with controlling compliance with the standards, including Rospotrebnadzor. The COVID-19 pandemic revealed a number of problems in the organization of work of inpatient departments, which required revision of the ways of rendering medical assistance. This article considers current sanitary and hygienic aspects of organization of operations at a general medicine ward, as well as the approaches to infection prevention in the context of medical care.

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COVID-19 pandemic: The testing times for healthcare workers

Abstract: Dear Editor,There is an increasing pressure on healthcare systems around the globe since the onset of the current coronavirus disease 2019 (COVID-19) pandemic to cope up with the increasing workload...

Cited by 4 publications

References 8 publications

Association of air pollution and coronavirus disease 2019 (COVID-19) in India

Association of air pollution and coronavirus disease 2019 (COVID-19) in India

Tocilizumab for COVID-19: A systematic review and meta-analysis of randomized controlled trials

Hygienic aspects of general medicine ward operation: problems and solutions

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