COVID-19 pneumonia, immunosuppression, and cytomegalovirus activation

Ghosh, Kinjalka

doi:10.4103/jpgm.jpgm_55_21

Journal of Postgraduate Medicine

2021

DOI: 10.4103/jpgm.jpgm_55_21

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COVID-19 pneumonia, immunosuppression, and cytomegalovirus activation

Kinjalka Ghosh

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Cited by 4 publications

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First case of concomitant cytomegalovirus (CMV) viremia in non‐immunocompromised COVID‐19 patient and ICU management strategy in Qatar with literature review

Iqbal

Arachchige

Ali

et al. 2022

Clinical Case Reports

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COVID-19 has created one of the world's worst pandemics and is associated with various life-threatening complications and infections, possibly due to various internal and external host factors. Cytomegalovirus (CMV) coinfection is one of those infections. We present a challenging case of severe COVID-19 infection managed in our ICU care facility with concomitant CMV infection. We aim to highlight the significance of early diagnosis and prompt management for a better outcome.

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First case of concomitant cytomegalovirus (CMV) viremia in non‐immunocompromised COVID‐19 patient and ICU management strategy in Qatar with literature review

Iqbal

Arachchige

Ali

et al. 2022

Clinical Case Reports

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COVID–19に関連したサイトメガロウイルス再活性化による空腸潰瘍出血の1例(Jejunal ulcer hemorrhage due to COVID–19–related cytomegalovirus reactivation: a case report)

知久,

明秀,

功佑

et al. 2023

Nihon Kyukyu Igakukai Zasshi: Japanese Journal of Japanese Asso

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要旨　症例は基礎疾患のない66歳の男性。前医で新型コロナウイルス感染症（COVID–19）と診断されて当センター紹介となった。SPO2 95%（室内気），CT検査で肺炎像は認めなかったが，CRP著明高値，高度腎機能障害，総リンパ球数減少を認めた。ステロイドは使用せず経過をみていたが，下血を繰り返し第28病日に多量の下血，出血性ショックとなったため造影CT検査を施行したところ，近位空腸に造影剤の血管外漏出像を認め，緊急手術で小腸部分切除術を施行した。病理組織学的にサイトメガロウイルス（cytomegalovirus: CMV）感染細胞が証明されたためCMV腸炎の確定診断となり，CMV–IgG抗体を保有していたことからCMV再活性化と考えられた。COVID–19によってサイトカインストームが引き起こされることにより後天的な免疫不全状態になることが報告されており，画像所見では説明のつかないCRP上昇や腎機能低下，総リンパ球数減少を認めた場合はCMV再活性化の可能性がある。COVID–19を診療する医師は，CMV再活性化を認知することが非常に重要である。

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Multiple drugs

2022

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COVID-19 pneumonia, immunosuppression, and cytomegalovirus activation

Cited by 4 publications

References 7 publications

First case of concomitant cytomegalovirus (CMV) viremia in non‐immunocompromised COVID‐19 patient and ICU management strategy in Qatar with literature review

First case of concomitant cytomegalovirus (CMV) viremia in non‐immunocompromised COVID‐19 patient and ICU management strategy in Qatar with literature review

COVID–19に関連したサイトメガロウイルス再活性化による空腸潰瘍出血の1例(Jejunal ulcer hemorrhage due to COVID–19–related cytomegalovirus reactivation: a case report)

Multiple drugs

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