COVID-19 Pneumonia: Three Thoracic Complications in the Same Patient

Borghesi, Andrea; Aggiusti, Carlo; Farina, Davide; Maroldi, Roberto; Muiesan, María Lorenza

doi:10.3390/diagnostics10070498

Cited by 9 publications

(6 citation statements)

References 20 publications

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“…However, the associated severity and prognosis of spontaneous pneumothorax concomitantly in COVID-19 infection has yet to be established [ 9 ]. Interestingly, in our case study and others, pneumothorax occurred days to weeks after onset of symptoms [ 1 , 2 , 3 , 4 , 5 , 6 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. Even though our patient did not present with evidence of cysts or bullae on initial CXR or CT, the delayed time frame to onset of pneumothorax could have given rise to pulmonary changes which predisposed him to pneumothorax.…”

Section: Discussionsupporting

confidence: 59%

Case report: Spontaneous pneumothorax in resolved, uncomplicated COVID-19 Pneumonia-A literature review

Dennison¹,

Carlson²,

Faehling³

et al. 2020

Respiratory Medicine Case Reports

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Section: Discussionsupporting

confidence: 59%

Case report: Spontaneous pneumothorax in resolved, uncomplicated COVID-19 Pneumonia-A literature review

Dennison¹,

Carlson²,

Faehling³

et al. 2020

Respiratory Medicine Case Reports

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“…Cases of spontaneous pneumothorax have been described in patients suffering from COVID-19 pneumonia . Pneumothoraces have been observed either as a first manifestation of the disease or in a later phase, especially in patients that necessitated orotracheal intubation and mechanical ventilation (31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46)(47)(48)(49). The aim of this study is to systematically review all the cases of spontaneous pneumothorax that occurred in otherwise healthy patients with no underlying lung disease and who were not put under invasive mechanical ventilation and detect similarities and differences comparing to spontaneous pneumothorax encountered before the emergence of this new entity.…”

Section: Introductionmentioning

confidence: 99%

Pneumothorax in otherwise healthy non-intubated patients suffering from COVID-19 pneumonia: a systematic review

Agrafiotis¹,

Rummens²,

Lardinois³

2021

J Thorac Dis

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Background: Cases of spontaneous pneumothorax have been described in patients suffering from coronavirus disease 2019 (COVID-19) pneumonia. The aim of this study is to systematically review all the cases of spontaneous pneumothorax that occurred in healthy patients with no underlying lung disease and who did not receive invasive mechanical ventilation.Methods: A PubMed research was conducted. The following data were collected: age, sex, side of the pneumothorax, smoking habit, time form onset of symptoms to the diagnosis of pneumothorax, the development of new bullous lesions on computed tomography and the type of treatment. In order to analyze the most homogeneous population possible, intubated patients were deliberately excluded. In total, 44 cases of spontaneous pneumothorax in otherwise healthy patients were taken into account. Since the available data were extracted from small observational studies, no particular bias risk assessment was performed.Descriptive statistics were used to synthesize results.Results: There were 37 male (84.1%) and 6 female (13.6%) patients. The majority of patients (66%) were treated only by chest tube thoracostomy, which most of the times resulted in a complete resolution of the pneumothorax. Simple surveillance was applied in 10 cases. Three patients underwent minimally invasive surgery. In 14 cases (31.8%) air-filled lesions were detected on imaging. Eleven patients received corticosteroids during their hospital stay. In the majority of cases (86.3%) the pneumothorax was resolved.Discussion: Even if the level of evidence, derived from case reports and small case series is low, the existence of a true secondary spontaneous pneumothorax due to SARS-CoV-2 should be recognized.Imaging techniques should be repeated throughout the clinical course of the patients in order to detect newly developed pulmonary complications. Surgical treatment is feasible and patients whose general condition permits, should be offered surgery according to the existing guidelines regarding spontaneous pneumothorax. National registries and databases are necessary in order to better understand the pathogenesis and complications of this novel entity.

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“…Only a few cases of encephalitis have been documented. COVID-19 severity seems to be linked to coagulopathy, which manifests as thrombosis in many organs [5,6].…”

Section: Coronavirus Disease Of 2019 (Covid-19mentioning

confidence: 99%

Evaluation of Drug Utilisation Pattern and Clinical Presentation in Covid19 Patients Based on the Disease Severity

Hema¹,

Moulika

Kukunuri³

et al. 2021

ijntps

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Coronavirus disease of 2019 (COVID-19) is an extremely communicable disease characterized by the serious acute respiratory influenza virus 2, a recently identified novel viral disease (SARS-CoV-2). Hitherto, the quantity of established instances worldwide has reached 135 million, and the number of deaths is 2.9 million. In India, the cases were found to be 20 million and the mortality rate is 3,51,000. This virus was first identified in Wuhan City, Hubei Province in China, at the end of 2019. Until now, it affected more than 200 countries. The treatment pattern and clinical presentations were assessed in COVID 19 patients. A total of 146 patients, severe patients (n = 71) and non-severe patients (n = 75) where included in the study. The mean age of the study population was found to be 58.76±14.32 and the most common symptoms of patients include fever, fatigue, dry cough, and diarrhea there is no statistically significant difference in the clinical features between severe and non-severe patients. There is no significant difference in the laboratory findings except lymphocyte count, CORADS and N/L ratio between severe and non-severe patients. COVID-19 affects all age groups especially the elderly. The risk for severe illness with COVID-19 increases with age. COVID 19 patients were presented with various the risk factors and the clinical features in the severe and non severe conditions patients, our study shows great significance to prevent the patient turning to critical condition during diagnosis and treatment.

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COVID-19 Pneumonia: Three Thoracic Complications in the Same Patient

Cited by 9 publications

References 20 publications

Case report: Spontaneous pneumothorax in resolved, uncomplicated COVID-19 Pneumonia-A literature review

Case report: Spontaneous pneumothorax in resolved, uncomplicated COVID-19 Pneumonia-A literature review

Pneumothorax in otherwise healthy non-intubated patients suffering from COVID-19 pneumonia: a systematic review

Evaluation of Drug Utilisation Pattern and Clinical Presentation in Covid19 Patients Based on the Disease Severity

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