COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus

Jan, Hasnain; Faisal, Shah; Khan, Ayyaz Ali; Khan, Salman; Usman, Hazrat; Liaqat, Rabia; Shah, Sajjad Ali

doi:10.15190/d.2020.5

Cited by 48 publications

(55 citation statements)

References 64 publications

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“…The mainstay treatment for COVID-19 is supportive management, with oxygen and mechanical ventilation, if needed (159). Empiric antibiotics have been used to prevent superimposed infections (160). FDA gave emergency use authorization for Remdesivir on May 1st, 2020, and there are no other FDA-approved medications available for COVID-19 (159)(160)(161)(162).…”

Section: Treatmentmentioning

confidence: 99%

Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks

et al. 2020

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Section: Treatmentmentioning

confidence: 99%

Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks

et al. 2020

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“…Pneumonia is a common result of COVID-19 that is variably treated with a regimen of medications that are currently undergoing clinical studies ( Figure 5) [5]. Although there is no FDA-approved medicinal therapy or vaccine for the novel coronavirus, this case illustrates that various drugs can be repurposed to treat COVID-19 patients on a temporary basis before an official medication is approved [6]. Before arriving at the emergency department, the patient received azithromycin, which was later seen to be ineffective by itself.…”

Section: Discussionmentioning

confidence: 99%

Hospital Course of a Man With Viral Pneumonia Caused by COVID-19

Solomon¹,

Ganti²

2020

Cureus

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The authors present a case of a man with pneumonia caused by COVID-19. There is currently no FDA-approved medical treatment or vaccine for COVID-19, so a variety of drugs and medicinal therapies have been repurposed for use in hospital settings and clinical studies while the medical community waits for a medication to be approved and standardized. Pneumonia is a common outcome of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), so cases of it are rapidly spreading around the world as the novel coronavirus continues to spread.

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“…This systematic review also identi ed the level of KAP on community-based intervention for preventing COVID-19 among participants in LMICs. Authors acknowledge other types of reviews (min-reviews, scoping, etc) conducted in area of COVID-19 (23,24). However, the current systematic review is unique in that its protocol is registered in a PROSPERO database, which is a register for systematic reviews.…”

Section: Discussionmentioning

confidence: 99%

Community-based interventions for preventing COVID-19 transmission in low- and middle-income countries:  A systematic review

Chisale

Ramazanu

et al. 2020

Preprint

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Background World Health Organisation (WHO) has approved and recommended several public health measures to halt the Coronavirus Disease 2019 (COVID-19) pandemic. The implementation of recommended interventions vary between higher income and Low and Middle-Income Countries (LMICs). The economical constraints within LMICs posed challenges in accessing resources for COVID-19 prevention. The study aimed to identify the workable community-based interventions being utilised in LMICs.Main body We applied systematic review approach for this study. Included articles were searched in eight online databases. The analysis was guided by the acceptable of best practice developed by the PROSPERO and COCHRANE for systematic search and selection of articles using pre-defined search terms. Furthermore, a PRISMA flow diagram was used to show the number of articles retrieved, retained, excluded with rationales given for every action. Studies conducted on community-based intervention for preventing COVID-19 and levels of knowledge, attitudes and practice (KAP) on community-based intervention for preventing COVID-19 regardless of the design were included. A mixed method appraisal tool (MMAT) was used to appraise studies.Six studies from LMICs were included for detail analysis after the systematic review screening process from 10,100 articles. The quality assessment using MMAT tool appraised these articles were all in highest quality. Among the six articles, 10 community-based interventions were implemented in LMICs. The three key workable and implemented interventions are: use of masks, social distance and hand wash. The review identified varying levels of KAP between LMICs and social-demographical factors affecting KAP in these settings.Conclusion This systematic review has identified the community-based interventions implemented in LMICs to prevent COVID-19 during the pandemic and key factors affecting the level of KAP among the population. This study re-affirms the importance of effective and suitable implementation of the identified interventions. More studies need to be conducted in LMICs to establish the effectiveness and adoption of the implemented and recommended interventions.

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COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus

Cited by 48 publications

References 64 publications

Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks

Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks

Hospital Course of a Man With Viral Pneumonia Caused by COVID-19

Community-based interventions for preventing COVID-19 transmission in low- and middle-income countries:  A systematic review

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COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus

Cited by 48 publications

References 64 publications

Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks

Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks

Hospital Course of a Man With Viral Pneumonia Caused by COVID-19

Community-based interventions for preventing COVID-19 transmission in low- and middle-income countries: &nbsp;A systematic review

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Community-based interventions for preventing COVID-19 transmission in low- and middle-income countries: A systematic review