COVID-19 severity in hospitalized patients with asthma: A matched cohort study

Robinson, Lacey B.; Fu, Xiaoqing; Bassett, Ingrid V.; Triant, Virginia A.; Foulkes, Andrea S.; Zhang, Yuqing; Camargo, Carlos A.; Blumenthal, Kimberly G.

doi:10.1016/j.jaip.2020.10.021

Cited by 26 publications

(19 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Those going on to experience LC28 had multisystem disease from the start, supporting the need for holistic care 10 . While asthma was not reported as a factor of risk for hospitalization in some studies 11 , its association with long COVID (LC28) warrants further investigation. Analysis of the pathophysiological drivers underlying the risk factors for long COVID identified here is a critical next step.…”

Section: Discussionmentioning

confidence: 95%

Attributes and predictors of long COVID

Sudre

Murray

Varsavsky

et al. 2021

Nat Med

1,969

224

1,792

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 95%

Attributes and predictors of long COVID

Sudre

Murray

Varsavsky

et al. 2021

Nat Med

1,969

224

1,792

View full text Add to dashboard Cite

“…Multivariable modeling was used in a subset of 24 studies of asthma and COVID-19 mortality (13,17,24,29,46,58,74,76,78,82,90,98,105,118,119,124,127,143,146,152,(155)(156)(157)(158), with adjustment for such factors as age, sex, ethnicity/race, education, and various comorbidities. These studies showed meta-odds ratio = 0.82 (95% CI, 0.79-0.85; P , 0.001), albeit with significant heterogeneity (I 2 = 59.1%; 95% CI, 29.7-72.9) (Table E2).…”

Section: Studies That Adjusted Relative Measures Of Association For Confounding Factorsmentioning

confidence: 99%

Asthma in Adult Patients with COVID-19. Prevalence and Risk of Severe Disease

Terry¹,

Heidel²,

Dhand

2021

Am J Respir Crit Care Med

View full text Add to dashboard Cite

Rationale: Health outcomes of people with coronavirus disease (COVID-19) range from no symptoms to severe illness and death. Asthma, a common chronic lung disease, has been considered likely to increase the severity of COVID-19, although data addressing this hypothesis have been scarce until very recently.Objectives: To review the epidemiologic literature related to asthma's potential role in COVID-19 severity.Methods: Studies were identified through the PubMed (MEDLINE) and medRxiv (preprint) databases using the search terms "asthma," "SARS-CoV-2" (severe acute respiratory syndrome coronavirus 2), and "COVID-19," and by cross-referencing citations in identified studies that were available in print or online before December 22, 2020.Measurements and Main Results: Asthma prevalence data were obtained from studies of people with COVID-19 and regional health statistics. We identified 150 studies worldwide that allowed us to compare the prevalence of asthma in patients with COVID-19 by region, disease severity, and mortality. The results of our analyses do not provide clear evidence of increased risk of COVID-19 diagnosis, hospitalization, severity, or mortality due to asthma.Conclusions: These findings could provide some reassurance to people with asthma regarding its potential to increase their risk of severe morbidity from COVID-19.

show abstract

“…Based on clinical and population-based studies, non-Hispanic Black and Latino individuals and communities are at increased risk for COVID-19 exposure [ 17 , 19 , 20 , 22 ], morbidity [ 8 , 9 , 23 , 24 ], and mortality [ 7 , 25 , 26 ]. Numerous chronic health conditions, including hypertension [ 8 , 23 , 26 - 29 ], diabetes [ 11 , 23 , 27 , 28 , 30 ], cancer [ 15 , 31 - 33 ], chronic obstructive pulmonary disease (COPD) [ 34 - 36 ] and asthma [ 28 , 37 - 39 ], and obesity [ 40 - 43 ] have been associated with an increased risk for poor COVID-19 outcomes.…”

Section: Introductionmentioning

confidence: 99%

Attitudes Toward Using COVID-19 mHealth Tools Among Adults With Chronic Health Conditions: Secondary Data Analysis of the COVID-19 Impact Survey

Camacho-Rivera¹,

Islam²,

Rivera³

et al. 2020

JMIR Mhealth Uhealth

View full text Add to dashboard Cite

Background Adults with chronic conditions are disproportionately burdened by COVID-19 morbidity and mortality. Although COVID-19 mobile health (mHealth) apps have emerged, research on attitudes toward using COVID-19 mHealth tools among those with chronic conditions is scarce. Objective This study aimed to examine attitudes toward COVID-19, identify determinants of COVID-19 mHealth tool use across demographic and health-related characteristics, and evaluate associations between chronic health conditions and attitudes toward using COVID-19 mHealth tools (eg, mHealth or web-based methods for tracking COVID-19 exposures, symptoms, and recommendations). Methods We used nationally representative data from the COVID-19 Impact Survey collected from April to June 2020 (n=10,760). Primary exposure was a history of chronic conditions, which were defined as self-reported diagnoses of cardiometabolic, respiratory, immune-related, and mental health conditions and overweight/obesity. Primary outcomes were attitudes toward COVID-19 mHealth tools, including the likelihood of using (1) a mobile phone app to track COVID-19 symptoms and receive recommendations; (2) a website to track COVID-19 symptoms, track location, and receive recommendations; and (3) an app using location data to track potential COVID-19 exposure. Outcome response options for COVID-19 mHealth tool use were extremely/very likely, moderately likely, or not too likely/not likely at all. Multinomial logistic regression was used to compare the likelihood of COVID-19 mHealth tool use between people with different chronic health conditions, with not too likely/not likely at all responses used as the reference category for each outcome. We evaluated the determinants of each COVID-19 mHealth intervention using Poisson regression. Results Of the 10,760 respondents, 21.8% of respondents were extremely/very likely to use a mobile phone app or a website to track their COVID-19 symptoms and receive recommendations. Additionally, 24.1% of respondents were extremely/very likely to use a mobile phone app to track their location and receive push notifications about whether they have been exposed to COVID-19. After adjusting for age, race/ethnicity, sex, socioeconomic status, and residence, adults with mental health conditions were the most likely to report being extremely/very or moderately likely to use each mHealth intervention compared to those without such conditions. Adults with respiratory-related chronic diseases were extremely/very (conditional odds ratio 1.16, 95% CI 1.00-1.35) and moderately likely (conditional odds ratio 1.23, 95% CI 1.04-1.45) to use a mobile phone app to track their location and receive push notifications about whether they have been exposed to COVID-19. Conclusions Our study demonstrates that attitudes toward using COVID-19 mHealth tools vary widely across modalities (eg, web-based method vs app) and chronic health conditions. These findings may inform the adoption of long-term engagement with COVID-19 apps, which is crucial for determining their potential in reducing disparities in COVID-19 morbidity and mortality among individuals with chronic health conditions.

show abstract

COVID-19 severity in hospitalized patients with asthma: A matched cohort study

Cited by 26 publications

References 6 publications

Attributes and predictors of long COVID

Attributes and predictors of long COVID

Asthma in Adult Patients with COVID-19. Prevalence and Risk of Severe Disease

Attitudes Toward Using COVID-19 mHealth Tools Among Adults With Chronic Health Conditions: Secondary Data Analysis of the COVID-19 Impact Survey

Contact Info

Product

Resources

About