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Introduction: The United States has the poorest health statistics of any high-income country. Political polarization has risen dramatically; newer safety net programs (the Affordable Care Act [ACA]) are unevenly provided because many Republican-leaning states refused expanded Federal coverage. Democratic programs have reduced physician leadership of medicine. Both have been deleterious. Here, we investigated associations among four key health measures two of which directly impact pregnancy outcomes and two that affect all patients by percentage of each state that voted for the Republican versus Democratic candidate in the 2020 presidential election. Methods: For each state, we used public, non-partisan databases to assess the incidence of COVID, maternal, and infant mortality per 100,000 population and average life expectancy. Correlations among these four outcome variables and percentage Republican vote were calculated (r), contextualized by measuring associations with related variables including COVID vaccination rates, access to medical care, and incidences of heart disease, obesity, diabetes, gunshot deaths, and automotive fatalities. Results: COVID mortality, maternal and infant mortality, and life expectancy were highly correlated with percentage Republican (“red”) vote per state. If “red” states had vaccination rates equivalent to Democratic-leaning (“blue”) states, 72,000 deaths could have been avoided. Overall, “red” states have lower health metrics, reduced access to care, and higher comorbidities. Conclusion: The percent Republican vote was strongly associated, but not the whole answer, for worse health outcomes for multiple key measures of public health including mortality, access to care, and various comorbidities. Overall, the ACA has improved patient access to care but has also led to “maternity care deserts” disproportionately in rural areas in “red” states. Translating insurance coverage into improved care and outcomes requires further analysis and will require multi-pronged approaches including expanding coverage and incentivizing quality care.
Introduction: The United States has the poorest health statistics of any high-income country. Political polarization has risen dramatically; newer safety net programs (the Affordable Care Act [ACA]) are unevenly provided because many Republican-leaning states refused expanded Federal coverage. Democratic programs have reduced physician leadership of medicine. Both have been deleterious. Here, we investigated associations among four key health measures two of which directly impact pregnancy outcomes and two that affect all patients by percentage of each state that voted for the Republican versus Democratic candidate in the 2020 presidential election. Methods: For each state, we used public, non-partisan databases to assess the incidence of COVID, maternal, and infant mortality per 100,000 population and average life expectancy. Correlations among these four outcome variables and percentage Republican vote were calculated (r), contextualized by measuring associations with related variables including COVID vaccination rates, access to medical care, and incidences of heart disease, obesity, diabetes, gunshot deaths, and automotive fatalities. Results: COVID mortality, maternal and infant mortality, and life expectancy were highly correlated with percentage Republican (“red”) vote per state. If “red” states had vaccination rates equivalent to Democratic-leaning (“blue”) states, 72,000 deaths could have been avoided. Overall, “red” states have lower health metrics, reduced access to care, and higher comorbidities. Conclusion: The percent Republican vote was strongly associated, but not the whole answer, for worse health outcomes for multiple key measures of public health including mortality, access to care, and various comorbidities. Overall, the ACA has improved patient access to care but has also led to “maternity care deserts” disproportionately in rural areas in “red” states. Translating insurance coverage into improved care and outcomes requires further analysis and will require multi-pronged approaches including expanding coverage and incentivizing quality care.
To assess the impact of inoculation of inactivated corona virus disease 2019 (COVID-19) vaccine on the outcome of frozen-thawed embryo transfer (FET). From January 2022 to November 2023, patients aged 20 ~ 45 years old undergoing FET at the Reproductive Medicine Center of a tertiary teaching hospital were prospectively enrolled. The patients were divided into vaccinated group (n = 458) and unvaccinated group (n = 530) based on the inoculation of inactivated COVID-19 vaccine before FET. Vaccinated group was further divided into three subgroups based on the dose (single dose, n = 55; double dose, n = 292; triple dose, n = 111) or interval from the first inoculation to FET (< 3 months, n = 51; 3 ~ 6 months, n = 101; > 6 months, n = 306). The primary outcome was live birth rate (LBR). The LBR (43.87% vs. 40.57%) was not significantly different between the vaccinated and unvaccinated groups, and so were embryo implantation rate (IR), clinical pregnancy rate (CPR), the gestational age at delivery and birth weight (P > 0.05). IR was significantly decreased with the shorter interval of vaccination (28.57% vs. 32.02% vs.45.24%, P = 0.007), while LBR and CPR were not significantly different (P > 0.05). For the dose subgroups of vaccination, IR, LBR and CPR were not significantly different (P > 0.05). Inoculation of inactivated COVID-19 vaccine did not affect the outcome of FET. Clinical Trial Registration Number: ChiCTR2200055597 (Chinese Clinical Trial Registry), January 14, 2022. (https://www.chictr.org.cn/bin/project/edit?pid=148312)
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