COVID-19 vaccination: the reality after clinical trials

Ruiz-Galiana, Julián; Ramos, Pilar; García‐Botella, Alejandra; García‐Lledó, Alberto; Gómez-Pavón, Javier; Castillo, Juan González del; Hernández-Sampelayo, Teresa; Martín-Delgado, M C; Sánchez, F J Martín; Martínez‐Sellés, Manuel; García, José María Molero; Guillén, Santiago Moreno; Rodríguez‐Artalejo, Fernando; Bouza, Emilio

doi:10.37201/req/035.2021

Cited by 1 publication

(2 citation statements)

References 42 publications

(56 reference statements)

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“…Although vaccination against COVID-19 is not mandatory in Spain, special emphasis should be placed on the ethics of responsibility [ 100 , 101 ].…”

Section: What Are the Ethical Aspects Of The Current Recommendation F...mentioning

confidence: 99%

“…The COVID-19 Committee of ICOMEM has pronounced in favor of vaccination in different published documents [ 100 ) ( 101 ]. However, despite the fact that there are sufficient legal grounds to support mandatory vaccination, the coercive path is not the most efficient, advocating intermediate positions that favor free vaccine adherence.…”

Section: What Are the Ethical Aspects Of The Current Recommendation F...mentioning

confidence: 99%

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COVID -19: On the threshold of the fifth year. The situation in Spain

Rodríguez-Artalejo,

Ruiz-Galiana,

Cantón

et al. 2023

Rev Esp Quimioter

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Despite having emerged from pandemic status, the incidence of COVID-19 episodes has recently increased in Spain, including pediatric cases and admissions to Intensive Care Units. Several recombinant variants are circulating among us, particularly XBB arising from two Omicron BA.2 sublineages with mutations in the genes encoding the spicule proteins that could increase binding to the ACE2 receptor and be more prone to immune escape. Faced with these, 3 pharmaceutical companies have developed vaccines adapted to the XBB.1.5 sublineage that are already available for administration in our setting with risks that should not be different from those of previous mRNA vaccines and with clearly favorable benefit/risk ratios. They should be applied to patients with potential for poor COVID-19 evolution and to collectives that have a particular relationship of proximity with them. Their application should be understood not only from a perspective of individual convenience but also from that of collective responsibility. The most convenient seems to be a simultaneous immunization of COVID-19 and influenza in our environment. In the therapeutic aspect, there is little to expect right now from antisera, but the already known antiviral drugs are still available and indicated, although their efficacy will have to be reevaluated due to their impact on populations that are mostly immunized and with a better prognosis than in the past. In our opinion, it is necessary to continue to make a reasonable and timely use of masks and other non-pharmacological means of protection.

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“…Although vaccination against COVID-19 is not mandatory in Spain, special emphasis should be placed on the ethics of responsibility [ 100 , 101 ].…”

Section: What Are the Ethical Aspects Of The Current Recommendation F...mentioning

confidence: 99%

Section: What Are the Ethical Aspects Of The Current Recommendation F...mentioning

confidence: 99%