COVID-19 vaccine acceptance and hesitancy among primary healthcare workers in Singapore

Koh, Sky Wei Chee; Liow, Yiyang; Loh, Victor Weng Keong; Liew, Seaw Jia; Chan, Yiong-Huak; Young, Doris

doi:10.1186/s12875-022-01693-z

Cited by 38 publications

(44 citation statements)

References 33 publications

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“…It is difficult to explain why mental health associated with attitude toward the COVID-19 vaccine, but worry/fear related COVID-19 pandemic increased depressive mood, anxiety, and lower resilience [36], and this relation may appear as acceptability and intention to the vaccination. [37,38]. We also observed a consistent pattern between worse mental health status and trust/intention toward the COVID-19 vaccine.…”

Section: E P U B a H E A D O F P R I N Tsupporting

confidence: 73%

Physical and mental health characteristics related to trust in and intention to receive COVID-19 vaccination: results from a Korean community-based longitudinal study

et al. 2022

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Objectives. To explore factors affecting attitudes toward COVID-19 vaccine, including sociodemographic characteristics and mental health status during the pandemic. Methods.Participants totaled 1,768, and were originally included in a community cohort study who responded to three online surveys related to COVID-19 (March 2020-March 2021. The K-means method was used to cluster trust and intention toward the COVID-19 vaccine.Baseline (2013-2018) sociodemographic characteristics, physical health status, and depressive symptoms were analyzed as exposure variables, and current mental health status was included in the analyses.Results. Most participants were classified into the moderate trust and high intention cluster (838, 47.4%); those with high trust and high intention accounted only for 16.86%. They tended to be older, had high-income level, and regular physical activity at baseline (p < 0.05); their sleep quality and psychological resilience were relatively high, compared to other groups. Conclusions.Our results suggest that more efforts are required to enhance the need and trust of COVID-19 vaccines.

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Section: E P U B a H E A D O F P R I N Tsupporting

confidence: 73%

Physical and mental health characteristics related to trust in and intention to receive COVID-19 vaccination: results from a Korean community-based longitudinal study

et al. 2022

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“…The attitude of 12,995 participants included in 8 studies was analyzed. The pooled proportion of the actual uptake of a COVID-19 vaccine booster dose was 31% (95% CI: 19–46%, I 2 = 100%), ranging from 2% (95% CI: 2–3%) [ 51 ] to 74% (95% CI: 71–77%) [ 56 ] ( Figure 4 ). After excluding the multicollinearity by correlation and the variance inflation factor (VIF), meta-regression succeeded in explaining 51% of this high heterogeneity with residual heterogeneity τ 2 = 0.46 (SE = 0.48).…”

Section: Resultsmentioning

confidence: 99%

COVID-19 Vaccine Booster Dose Acceptance: Systematic Review and Meta-Analysis

et al. 2022

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The World Health Organization (WHO) recommended coronavirus disease 2019 (COVID-19) booster dose vaccination after completing the primary vaccination series for individuals ≥18 years and most-at-risk populations. This study aimed to estimate the pooled proportion of COVID-19 vaccine booster dose uptake and intention to get the booster dose among general populations and healthcare workers (HCWs). We searched PsycINFO, Scopus, EBSCO, MEDLINE Central/PubMed, ProQuest, SciELO, SAGE, Web of Science, Google Scholar, and ScienceDirect according to PRISMA guidelines. From a total of 1079 screened records, 50 studies were extracted. Meta-analysis was conducted using 48 high-quality studies according to the Newcastle-Ottawa Scale quality assessment tool. Using the 48 included studies, the pooled proportion of COVID-19 vaccine booster dose acceptance among 198,831 subjects was 81% (95% confidence interval (CI): 75–85%, I2 = 100%). The actual uptake of the booster dose in eight studies involving 12,995 subjects was 31% (95% CI: 19–46%, I2 = 100%), while the intention to have the booster dose of the vaccine was 79% (95% CI: 72–85%, I2 = 100%). The acceptance of the booster dose of COVID-19 vaccines among HCWs was 66% (95% CI: 58–74%), I2 = 99%). Meta-regression revealed that previous COVID-19 infection was associated with a lower intention to have the booster dose. Conversely, previous COVID-19 infection was associated with a significantly higher level of booster dose actual uptake. Subgroup analyses revealed that the pooled booster dose acceptance in the WHO region of the Americas, which did not include any actual vaccination, was 77% (95% CI: 66–85%, I2 = 100%). The pooled acceptance of the booster dose in the Western Pacific was 89% (95% CI: 84–92%, I2 = 100), followed by the European region: 86% (95% CI: 81–90%, I2 = 99%), the Eastern Mediterranean region: 59% (95% CI: 46–71%, I2 = 99%), and the Southeast Asian region: 52% (95% CI: 43–61%, I2 = 95). Having chronic disease and trust in the vaccine effectiveness were the significant predictors of booster dose COVID-19 vaccine acceptance. The global acceptance rate of COVID-19 booster vaccine is high, but the rates vary by region. To achieve herd immunity for the disease, a high level of vaccination acceptance is required. Intensive vaccination campaigns and programs are still needed around the world to raise public awareness regarding the importance of accepting COVID-19 vaccines needed for proper control of the pandemic.

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“…Nurses have the most direct contact with patients of any healthcare workers, and they are typically more directly confronted with the public's vaccine apprehension. However, recent studies have shown that nurses are even more hesitant about vaccines than other health professionals in Singapore (nurses: 7.4% vs. physicians: 0%) ( 19 ), Chicago (nurses: 27.0% vs. physicians or advanced practitioners: 1.7%) ( 20 ), Cape Town (nurses: 49.2% vs. physicians: 10.2%) ( 21 ), and Kuwait (nurses: 29.2% vs. physicians: 9.6%) ( 22 ). In fact, the issue of high vaccine hesitancy rates among nurses can no longer be ignored according to the data in Turkey (68.6%), Hong Kong (63%), and Israel (61%) ( 23 – 25 ).…”

Section: Introductionmentioning

confidence: 99%

Targeting COVID-19 vaccine hesitancy among nurses in Shanghai: A latent profile analysis

Zhang

Dai

Wang

et al. 2022

Front. Public Health

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ObjectivesThis study aims to clarify the profiles of the psychological antecedents of vaccine hesitancy among Shanghai nurses with a person-centered approach.MethodsA population-based cross-sectional online survey was conducted on Shanghai nurses from July to August 2021 (N = 1,928). In the online survey, participants were asked to report their sociodemographic, the 5C vaccine hesitancy components, their knowledge level of COVID-19 vaccine and vaccination, and the COVID-19 vaccination uptake intention and attention to vaccine news. Latent profile analysis was used to reveal distinct profiles of vaccine hesitancy.ResultsThe results revealed four profiles, including “believers” (68.9%; high confidence and collective responsibility), “free riders” (12.7%; similar characteristics to believers, except for a low collective responsibility), “middlemen” (14.6%; middle in all 5C constructs), and “contradictors” (3.7%; high in all 5C constructs). Compared to believers, middlemen were younger, more likely to be female, childless, less educated, held lower professional titles, had fewer years of nursing service, sometimes or never complied with recommended vaccinations, had satisfactory or poor self-assessed health status, had no work experience during the COVID-19 epidemic, and possessed greater levels of knowledge. Free riders were more likely to work in community health centers and have a lower degree than believers. Contradictors were more likely to work in community health centers, had junior college degrees or lower, and had no work experience during the COVID-19 epidemic than believers. From the highest to the lowest on vaccination intention and attention to vaccine news were believers, then free riders, contradictors, and finally middlemen.ConclusionThis study could aid in the development of personalized vaccination strategies based on nurses' vaccine hesitancy profiles and predictors. In addition to vaccine believers, we identified other three profiles based on their 5C psychological antecedents, emphasizing the significance of establishing tailored vaccination campaigns. Further research into the prevalence of profile structure in other groups of healthcare workers is required.

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COVID-19 vaccine acceptance and hesitancy among primary healthcare workers in Singapore

Cited by 38 publications

References 33 publications

Physical and mental health characteristics related to trust in and intention to receive COVID-19 vaccination: results from a Korean community-based longitudinal study

Physical and mental health characteristics related to trust in and intention to receive COVID-19 vaccination: results from a Korean community-based longitudinal study

COVID-19 Vaccine Booster Dose Acceptance: Systematic Review and Meta-Analysis

Targeting COVID-19 vaccine hesitancy among nurses in Shanghai: A latent profile analysis

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