COVID-Inconfidentes - SARS-CoV-2 seroprevalence in two Brazilian urban areas in the fourth quarter 2020: study protocol and initial results

Abstract

Objective: To describe study protocol and initial results of research project COVID-Inconfidentes. Method: This paper described the methodological procedures adopted and the prevalence of the SARS-CoV-2 infection in the population. A household survey was conducted between October and December 2020, in two historic cities of Brazil's mining region. Anti-SARS-CoV-2 antibody was detected using the Wondfo® rapid test. The face-to-face interview consisted of administration of a questionnaire containing registration data, sociodemographic and economic variables, living habits, general health condition, mental health, sleep habits, and eating and nutrition. Results: We evaluated 1,762 residents, of which 764 (43.4 %) were in Mariana and 998 (56.6 %) in Ouro Preto. For both cities, 51.9 % of the interviewees were female, with a predominance of the age range 35 to 59 years old (47.2 %). The prevalence of the SARS-CoV-2 infection was 5.5 % in both cities, 6.2 % in Ouro Preto, and 4.7 % in Mariana (p-value > 0.05). Conclusion: The study was effective to estimate the seroprevalence of infection by the virus and its findings will enable further analyses of the health conditions of the population related to social isolation and the risk of infection with SARS-CoV-2.

The Interaction between Education and Sex with Alcohol Consumption during the COVID-19 Pandemic: A Cross-Sectional Analysis of Two Brazilian Cities

“…Participants eligible for the study were permanent residents of households in the urban areas of the municipalities, aged ≥ 18 years, who consented to participate in the study. Individuals with compromised cognitive function, difficulty in responding to the questionnaire, or inability to provide blood samples due to difficulties with venous access were excluded [ 29 ].…”

“…The sampling weight of each selected unit (census sector, household, and individual) was calculated to correlate with the 2019 population projection. For more details on the sample calculation and field logistics, see Meireles et al [ 29 ]. A total of 1789 individuals were recruited, of which 27 (1.5%) were excluded for not completing the interview or not collecting a blood sample, totaling 1762 individuals, of which 764 were from the municipality of Mariana (43.4%) and 998 from Ouro Preto (56.6%).…”

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“…This study followed reported guidelines dictated by the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE). For more details on data collection, see Meireles et al 14 .…”