Cow's Milk Antibodies and Coronary Heart Disease

Davies, D.F.; Rees, B.; Davies, PaulT.G.

doi:10.1016/s0140-6736(80)91648-7

Cited by 11 publications

(3 citation statements)

References 6 publications

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“…Again, interest was aroused and, again, the findings were promptly refuted by others (Gibney et al, 1980;Scott, Swinburne, McGuffin, & Losowsky, 1976;Toivanen, Viljanen, & Svilahti, 1975). Nevertheless, Davies and coworkers went on to show that anti-milk antibodies, as detected in their haemagglutination assay, were directed to the bovine MFGM (Davies, 1984;Davies, Rees, & Davies, 1980, 1982. They proposed that anti-bovine MFGM antibodies might cross react with platelet membrane antigens, inducing platelet aggregation and hence atherogenesis.…”

Section: Milk Xor Anti-xor Antibodies and Atherosclerosismentioning

confidence: 99%

Milk xanthine oxidase: Properties and physiological roles

Harrison

2006

International Dairy Journal

112

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Section: Milk Xor Anti-xor Antibodies and Atherosclerosismentioning

confidence: 99%

Milk xanthine oxidase: Properties and physiological roles

Harrison

2006

International Dairy Journal

112

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“…They are also sources of minerals like potassium, magnesium and calcium. Milk protein has been implicated in a study reporting elevated levels of antibodies to milk protein in patients of myocardial infarction in comparison with healthy controls 116 . Dairy consumption has been correlated positively, in an ecological study, with blood cholesterol as well as coronary mortality.…”

Section: Dairy Productsmentioning

confidence: 99%

Diet, nutrition and the prevention of hypertension and cardiovascular diseases

Reddy

Katan

2004

Public Health Nutr.

377

204

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Cardiovascular diseases (CVD) are growing contributors to global disease burdens, with epidemics of CVD advancing across many regions of the world which are experiencing a rapid health transition. Diet and nutrition have been extensively investigated as risk factors for major cardiovascular diseases like coronary heart disease (CHD) and stroke and are also linked to other cardiovascular risk factors like diabetes, high blood pressure and obesity. The interpretation of evidence needs to involve a critical appraisal of methodological issues related to measurement of exposures, nature of outcome variables, types of research design and careful separation of cause, consequence and confounding as the basis for observed associations. Adequate evidence is available, from studies conducted within and across populations, to link several nutrients, minerals, food groups and dietary patterns with an increased or decreased risk of CVD. Dietary fats associated with an increased risk of CHD include trans-fats and saturated fats, while polyunsaturated fats are known to be protective. Dietary sodium is associated with elevation of blood pressure, while dietary potassium lowers the risk of hypertension and stroke. Regular frequent intake of fruits and vegetables is protective against hypertension, CHD and stroke. Composite diets (such as DASH diets, Mediterranean diet, 'prudent' diet) have been demonstrated to reduce the risk of hypertension and CHD. Sufficient knowledge exists to recommend nutritional interventions, at both population and individual levels, to reduce cardiovascular risk. That knowledge should now be translated into policies which promote healthy diets and discourage unhealthy diets. This requires coordinated action at the level of governments, international organizations, civil society and responsible sections of the food industry.

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“…Previous work [19][20][21] on the detection of IgG anti-FGM in the sera of coronary heart patients do not indicate whether or not the FGM antigen is distinct from the other milk proteins. Therefore we have considered the possibility that antibodies of other immunoglobulin classes or sub-classes might be reactive with an FGM antigen that is distinct from casein.…”

Section: Discussionmentioning

confidence: 99%

IgE and IgG4 antibodies to bovine milk fat globule membrane in atopic eczema patients: a study of their occurrence, relevance and antigenic specificity

Shakib¹,

Brown²,

R³

et al. 1985

Clin Experimental Allergy

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IgE and IgG4 antibodies to bovine milk fat globule membrane (FGM) were measured in atopic eczema patients to determine whether their presence would account for allergy to milk in cases where whole or individual milk protein-specific antibodies are not detectable. The study demonstrates that the measurements of IgE and IgG4 antibodies to EGM do not offer any additional diagnostic value in milk exacerbated cases ofatopie eczema. Furthermore, cross-inhibition studies with four milk proteins showed that these FGM-reactive IgE and IgG4 antibodies are directed against a-casein.

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Cow's Milk Antibodies and Coronary Heart Disease

Cited by 11 publications

References 6 publications

Milk xanthine oxidase: Properties and physiological roles

Milk xanthine oxidase: Properties and physiological roles

Diet, nutrition and the prevention of hypertension and cardiovascular diseases

IgE and IgG4 antibodies to bovine milk fat globule membrane in atopic eczema patients: a study of their occurrence, relevance and antigenic specificity

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