Cowside Antibiotic Residue Testing

Abstract

Detectable concentrations of antibiotic residues in milk supplies are illegal. They interfere with manufacturing of some dairy products, may cause hypersensitivity or resistance to drug therapy in humans, and are perceived by consumers as undesirable. Antibiotics are used for intramammary, intramuscular, oral, or reproductive therapy to counter acute or subacute diseases. Residues can result for many reasons, including poor records of treatment, failure to observe recommended label withdrawal time, prolonged drug clearance, treated animal identification problems, products not used according to label directions, lack of advice on withdrawal period, and others. Several effective and useful on-farm residue screening tests are available and should be used to monitor cows treated with an antibiotic for any reason. Herds that use drugs without label directions or that do not follow label directions should find these tests valuable. Producers must understand how to interpret the results of these tests. Also, dairy farmers must recognize if the selected test method is capable of detecting those antibiotics in use and what are to be monitored.

Effects of intrauterine infusion of povidone-iodine on endometrial cytology and bacteriology in dairy cows with clinical endometritis

“…Many therapeutic methods are employed, including the administration of hormones, such as prostaglandin F 2α (PGF 2α ) or estradiol, intrauterine infusions of antibiotics [ 14 ] or povidone-iodine (polyvinylpyrrolidone-iodine or PVP-I) [ 17 , 18 , 19 , 26 ]. For problems with residual hormones or antibiotics [ 10 , 20 ], antibiotic-resistant bacteria [ 9 ] and withdrawal periods, safe and proper treatments to treat these uterine diseases are needed. Conversely, PVP-I has advantages that it does not require a withdrawal period and does not pass into the milk except in the case of excess administration [ 1 , 2 ].…”

Sütlerde Antibiyotik Kalıntılarının Belirlenmesi

“…Residues are of concern due to their possible adverse effects on people allergic to antibiotics, potential buildup of antibioticresistant organism in humans and inhibition of starter cultures used to produce cultured milk products such as yogurt and cheeses 3,4 . These reasons make it important to effectively control antibiotic residues in milk and therefore, regulatory authorities have enacted maximum residue limits (MRLs) for a number antiinfective agent in milk.…”

Resíduos De Antibióticos No Leite: Causas E Impactos Para a Indústria E Saúde Pública

“…Os antimicrobianos e seus metabólicos podem depositar-se ou acumular-se nas células, nos tecidos ou nos órgãos do animal e, quando vestígios dessas substâncias são detectadas posteriormente nos alimentos, são denominadas de resíduos (BRITO, 2000). Outras causas para que se constatem resíduos de antimicrobianos no leite são: falhas na observação ou não cumprimento dos períodos de carência dos antimicrobianos administrados, uso de dosagem acima da recomendada, uso de medicamentos por períodos muito prolongados, uso de medicamentos com períodos de excreção prolongados ou mistura acidental de leite não contaminado com leite contaminado, ocasionado por problemas ou falhas na identificação dos animais tratados (JONES;SEYMOUR, 1988). Outra condição, que pode determinar a presença de resíduos no leite, é a adição intencional de drogas para encobrir a deficiência na qualidade higiênica do leite, visando aumentar seu tempo de vida útil (BRASIL, 1993).…”