CP-152 Appropriateness of art prescription in hiv infected naïve patients according to the gesida guide (gesida/spanish aids national plan recommended guidelines)

Abstract

BackgroundProper management of HIV treatment is important because of the complexity and speed with which knowledge changes, requiring the development of guidelines for antiretroviral therapy (ART), but also frequent updating of these guidelines. In Spain, the Society of Infectious Diseases annually produces a consensus document (GESIDA) for ART.PurposeThe aim of this study was to evaluate adjustment to the recommendations of the GESIDA consensus document in Spain for the prescription of ART in naïve patients between January 2014 and March 2016.Material and methodsThis was a retrospective observational study. The medical records of all HIV naïve adult patients were reviewed. Epidemiological and laboratory data on viral load (blood VL) and CD4+ were retrieved from the clinical management programme. Therapeutic regimens at treatment initiation and clinical data were collected. A descriptive statistical analysis was performed. A central tendency was expressed, with median and minimum and maximum values.ResultsBetween 2014 and March 2016, 28 patients were started on ART; 18 (85.7%) were men, mean age was 43.13 years (IQR 24–64), blood VL was 94 396 copies/mL (IQR 800–749 000) and CD4 was 384.5 cells/mm3 (IQR 11–850). The treatments described in the Guide were prescribed to 27 patients (96%). 7 (25%) received a preferred treatment to the Guide, 20 (71%) an alternative treatment described from the Guide and only 1 patient received a therapeutic regimen not described in the Guide for a justified reason.ConclusionThe initial prescription for a naïve HIV patient during the period of this study was conducted in accordance with the recommendations from GESIDA.References and/or acknowledgementsSpanish AIDS National Plan recommended guidelines, 2014, 2015, 2016.No conflict of interest