Features of microstructure, mechanical properties, and cracking behaviour of the René 80-type superalloy manufactured by laser-based directed energy deposition (DED-LB) have been investigated. Different cracking behaviours were observed in two thin walls fabricated by DED-LB under different conditions. The defect-free thin wall was produced at low power and scanning speed, while increasing energy input during the process led to intensive cracking. Two types of cracks that developed in the René 80-type superalloy were identified: solidification hot cracking and ductility-dip cracking (DDC), caused by σ-phase particles. It was found that transition from an equiaxed structure to a columnar one increased the susceptibility to crack propagation.