2020
DOI: 10.7759/cureus.7379
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Cracking the Case of Achalasia-induced Syncopal Episode

Abstract: Achalasia is an uncommon disease that occurs due to inability of lower esophageal sphincter from relaxing, leading to dysphagia to liquids and solids. Clues to this diagnosis include: failed treatment with proton pump inhibitors, and changes on imaging studies including chest X-ray and barium esophagogram. Ultimately it is a diagnosis made on esophageal manometry. Swallow-induced syncope has been known in patients with achalasia for almost three centuries. Here we present the case of a patient with achalasia a… Show more

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“…When an ARSA passes over the esophagus, it can lead to esophageal compression and dilation [ 14 , 18 ]. In response to the dilation of the esophagus, afferent fibers of the vagus nerve are stimulated through mechanoreceptors [ 28 , 29 ]. In the present case, chronic stimulation of the vagus nerve, induced by anomalous vessel-associated esophageal dilation, might have been the underlying cause of HO.…”
Section: Discussionmentioning
confidence: 99%
“…When an ARSA passes over the esophagus, it can lead to esophageal compression and dilation [ 14 , 18 ]. In response to the dilation of the esophagus, afferent fibers of the vagus nerve are stimulated through mechanoreceptors [ 28 , 29 ]. In the present case, chronic stimulation of the vagus nerve, induced by anomalous vessel-associated esophageal dilation, might have been the underlying cause of HO.…”
Section: Discussionmentioning
confidence: 99%