Life cycle assessment (LCA) is becoming an increasingly important environmental systems analysis tool in the construction sector for the identification of measures and strategies to reduce the environmental impact of buildings throughout the whole value chain. Geotechnical processes, such as earthworks, ground improvement and foundation construction, are often energy- and resource-intensive. Geotechnical works can thus play an important role in moving towards more sustainable building construction practices. This article reviews recent applications of LCA of buildings, including foundations as the focus or part of the system studied, based on the ISO 14040/44 standards. The system boundaries of geotechnical works are defined and a conceptual model for LCA of geotechnical works in building construction is proposed. The results of the literature review showed that the application of LCA to the building substructure is currently under development, but still in a fragmented state. There is a need for a unified framework for LCA of geotechnical works in building construction, especially regarding the definition of the functional unit, the choice of system boundaries, the appropriateness of inventory data, and the selection of impact categories. The conceptual model focuses on the demonstration of inventory flows and system boundaries and can serve as a basis for scope definition in future LCA studies of geotechnical works in building construction. It may also support effective communication between different actors and stakeholders regarding environmental sustainability in the construction sector.