Cranberry capsules to prevent nosocomial urinary tract bacteriuria after pelvic surgery: a randomised controlled trial

Abstract

PAC prophylaxis does not reduce the risk of postoperative bacteriuria in patients undergoing pelvic surgery.

A Comprehensive Review of the Confirmed Therapeutic Effects of Grape Seed Extracts, Cranberry Juice, and Proanthocyanidins in Human Beings

“…The fundamental outcome was after surgery, the urine bacterial count was estimated after 15 and 40 days. Pretreatment of cranberry proanthocyanidins did not decrease the occurrence of UTIs (Letouzey et al, 2017) .…”

Authors' reply re: Cranberry capsules to prevent nosocomial urinary tract bacteriuria after pelvic surgery: a randomised controlled trial

“…We appreciate the comment from Henry Botto and Amy B. Howell on our article ‘Cranberry Capsules to Prevent Nosocomial Urinary Tract Bacteriuria after Pelvic Surgery’ . They expressed concerns that the study was underpowered.…”

“…We appreciate the comment from Henry Botto and Amy B. Howell 1 on our article 'Cranberry Capsules to Prevent Nosocomial Urinary Tract Bacteriuria after Pelvic Surgery'. 2 They expressed concerns that the study was underpowered. As we acknowledged in the article, the required patient number was not reached at the primary study endpoint; however, as a trend for lower rates for bacteriuria was observed for the placebo group in our cohort, the results would not be expected to reverse with a larger sample size.…”

“…Current techniques of urinary diversion range from a uretero-ileo-cutaneostomy to detubularised ileal or ileocolonic segments to create continent diversions or orthotropic neobladders. 2 This study has a…”

Re: Cranberry capsules to prevent nosocomial urinary tract bacteriuria after pelvic surgery: a randomised controlled trial: Cranberry for prevention of bacteriuria?

“…The recent study by Letouzey et al 1 in BJOG concluded that administering cranberry containing 36 mg of proanthocyanidin postoperatively does not reduce the risk of postoperative bacteriuria in patients receiving short-term transurethral catheterisation after pelvic surgery. However, significant methodological issues with the study confound this conclusion.…”