Cranial Nerve Palsies in Renal Osteodystrophy

Abid, Farida; Lalani, Irfan; Zakaria, Asma; Facchini, Sergio; Hunter, Jill V.

doi:10.1016/j.pediatrneurol.2006.07.009

Cited by 7 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Leontiasis ossea is an uncommon presentation of renal osteodystrophy. It causes foraminal stenosis in the skull base, leads to upper airway obstruction or cranial nerve compressions such as facial palsy or hearing loss (8)(9)(10). In typical presentations, clinical and laboratory data which may facilitate the diagnosis and biopsy is rarely necessary.…”

Section: Discussionmentioning

confidence: 99%

Leontiasis ossea; a rare presentation of secondary hyperparathyroidism

Jelodar¹,

Yarmohamadi²,

Wadji³

et al. 2018

J Renal Inj Prev

View full text Add to dashboard Cite

Uremic leontiasis ossea (ULO) can cause life-threatening upper airway obstruction and compressive cranial neuropathy. Hence, early recognition and treatment of leontiasis ossea can prevent its complications. Please cite this paper as: RaffieiJelodar H, Yarmohamadi M, Baghai Wadji M, Babaei MR. Leontiasis ossea; a rare presentation of secondary hyperparathyroidism. J Renal Inj Prev. 2018;7(4):321-323.Leontiasis ossea is a rare presentation of renal osteodystrophy with few reports in literature. It causes severe skeletal deformity in the cranial bones. This study presents a report on a patient with advanced hyperparathyroidism with skeletal changes compatible with leontiasis ossea. The patient was a 34-year-old man with end-stage renal disease, uncontrolled hypertension, and dyspnea who was referred to our hospital. Physical examinations revealed: toggled speech (nasal speech), mouth breathing and facial change, saddle nose, nares widening, increased interdental space and mandibular enlargement. His serum intact parathyroid hormone (iPTH) level was 3199 pg/mL, Paranasal sinuses CT scan showed a significant expansion of the mandibular, maxillary and skull bones. Parathyroid sonography reported two severe hypertrophied parathyroid glands. The patient underwent total parathyroidectomy as a result of symptomatic bone involvement.

show abstract

Section: Discussionmentioning

confidence: 99%

Leontiasis ossea; a rare presentation of secondary hyperparathyroidism

Jelodar¹,

Yarmohamadi²,

Wadji³

et al. 2018

J Renal Inj Prev

View full text Add to dashboard Cite

show abstract

“…RO is in the differential diagnosis of multiple cranial nerve palsies. 10 However, compression of optic nerves secondary to narrowing of optic canals is extremely rare in RO. There is only one prior report of optic nerve compression as a result of RO 2 in a patient who was treated with high-dose corticosteroids followed by optic canal decompression surgery for one eye, which resulted in significant visual field restoration.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Compressive Optic Neuropathy from Renal Osteodystrophy Caused by Branchio-oto-renal Syndrome Stabilised After Parathyroidectomy

Sundaram

Abhayambika

Kumar

2017

Neuro-Ophthalmology

View full text Add to dashboard Cite

Renal osteodystrophy can cause calvarial hypertrophy and narrowing of the neural canals and foramina. Compressive optic neuropathy is extremely rare in renal osteodystrophy and was reported once only. The authors report bilateral, simultaneous compressive optic neuropathy secondary to renal osteodystrophy with features of uremic leontiasis ossea in chronic renal failure caused by branchio-oto-renal syndrome. Because of the extensive calvarial hypertrophy and the surgical difficulties envisaged with optic canal decompression, conservative approach was pursued. The patient's visual acuity and fields improved after partial parathyroidectomy. Visual improvement may be explained by the arrest of renal osteodystrophy and reduced optic nerve compression after parathyroidectomy.

show abstract

“…nerve compression such as facial palsy or hearing loss [8][9][10]. In those cases surgical nerve decompression must be considered.…”

mentioning

confidence: 99%