2009
DOI: 10.1016/j.amjoto.2007.12.007
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Craniocervical necrotizing fasciitis with and without thoracic extension: management strategies and outcome

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Cited by 34 publications
(35 citation statements)
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“…Its most common factor is Streptococcals. Anaerobic pathogens were identified in 30% of patients [6,7]. Streptococcal spp formed in the culture of our case.…”
Section: Discussionmentioning
confidence: 54%
See 1 more Smart Citation
“…Its most common factor is Streptococcals. Anaerobic pathogens were identified in 30% of patients [6,7]. Streptococcal spp formed in the culture of our case.…”
Section: Discussionmentioning
confidence: 54%
“…In general, hypocalcemia is seen in patients during the disease, as fatty acids, formed during subcutaneous fat necrosis, combine with calcium to form soap. Hyperbaric oxygen and intravenous immune globulin treatment decreases the mortality rate [6,7,10].…”
Section: Discussionmentioning
confidence: 99%
“…When necrotizing infections involve the head and neck, it is termed craniocervical necrotizing fasciitis (CCNF) and is associated with significant morbidity and mortality usually due to septic shock, disseminated intravascular coagulation (DIC), and organ failure [3]. In the prehyperbaric oxygen (pre-HBO) era, standard of care included early recognition of the disease, aggressive antibiotic treatment, and repetitive surgical debridement [3]. The clinical manifestations usually begin rather quiescently; the affected area becomes swollen and erythematous, and the patient has a low-grade fever.…”
Section: Discussionmentioning
confidence: 99%
“…Initial antibiotherapy should be covered combination of aerobic gram-positive and gram-negative organisms and anaerobes such as a combination of penicillin, aminoglycoside (if renal function permits), and clindamycin. Hyperbaric oxygen treatment and high-dose polyspecific intravenous immunoglobulin, along with antimicrobials and a surgical approach are other treatment options [20]. We sent all of the patients to operation room for cervicofacial exploration and debridement promptly.…”
Section: Accepted Manuscriptmentioning
confidence: 99%