Craniofacial hyperhidrosis can usually be managed pharmacologically, but surgery may sometimes be needed

Abstract

Craniofacial hyperhidrosis, which refers to excess sweating affecting the forehead and face, may negatively affect health-related quality of life. Based on the current evidence, first-line treatments include oral and/or topical anticholinergics or intradermal botulinum toxin A. Patients who do not respond to pharmacological therapy may benefit from endoscopic thoracic sympathectomy or one of its variations. However, such surgery is often associated with high rates of troublesome and embarrassing compensatory sweating.