The purpose of this study was to examine the acute effects of oral creatine hydrochloride (CrHCl) supplementation on three repeated bouts of bench press and vertical jumping exercises and body composition measures (body weight (BW), fat-free mass (FFM) and fat mass (FM)). Methods: Fifteen resistance trained males completed 3 sets of the barbell bench press (70% 1RM) and 3 sets of the repeated counter-movement vertical jump (CMJ; 85% maximal CMJ height), with 2 min rest between sets, before and after a 7 d CrHCl intervention (4 g·day -1 ). A two-factor repeated measures ANOVA was used to determine significant main effects (time and set) with post-hoc Bonferroni analysis and interaction effects (time x set) for bench press and CMJ performances from pre-to post-intervention. A one-factor repeated measures ANOVA was used to assess pre-to post-intervention differences in body composition. Results: Significant main and interaction effects for time and set were found in the bench press from pre-to postintervention (p < 0.005, for all) with Bonferroni analysis indicating increased performance on later sets (eg, Set 3 > Set 2 > Set 1, p < 0.005). Significant main effects for time and set were found in the CMJ test from pre-to post-intervention (p < 0.005) but no interaction effect was found (p > 0.05). Post hoc analysis indicated increased performance on later sets. BW was the only body measure to reach significance (p < 0.005). Conclusion: Supplementation with 4 g of CrHCl for 7 d in healthy, resistance trained men significantly increased the number of repetitions performed during intermittent bouts of submaximal bench press and CMJ exercises and body weight.